James H Brashears

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PURPOSE Accelerated partial breast irradiation (APBI) with the MammoSite breast brachytherapy (MBB) system is being investigated as an alternative to whole breast radiation in breast conservation therapy (BCT) at multiple centers worldwide. The newness of MBB means a complete understanding of long-term toxicity, particularly involving the chest wall, has(More)
PURPOSE We performed a retrospective study of patients with diffuse pontine glioma (DPG) who suffered neuraxis metastasis (NM) and characterized the incidence, clinical features, radiologic findings, and patterns of disease dissemination. METHODS Magnetic resonance imaging (MRI) of brain and spine was used to assess NM. Some patients also underwent(More)
PURPOSE Although ablative technologies, including radio frequency (RF) ablation (RFA) and cryoablation (CA), are being used to treat renal masses, complications associated with injury to vital renal structures are not well understood. We investigated these worst case scenarios by deliberately targeting vital renal structures with CA or RFA in a porcine(More)
OBJECTIVES To describe 6 cases of rectourethral fistula in patients treated with brachytherapy plus external beam radiotherapy for localized prostate cancer and subsequent rectal biopsies or rectal surgery. METHODS A retrospective chart review was undertaken of patients with prostate cancer treated with brachytherapy who presented to our institution with(More)
OBJECTIVES To determine the effect of prior benign prostate biopsies on the surgical and clinical outcomes of patients treated with radical perineal prostatectomy for prostate cancer. METHODS A total of 1369 patients with clinically localized prostate cancer underwent radical prostatectomy by a single surgeon between 1991 and 2001. A subset of 203(More)
Radiation necrosis is a known sequela of delivering high doses of ionizing radiation to the central nervous system and may be confused with tumor recurrence. Although stereotactic radiation has found increasing application in managing central nervous system malignancies, the imaging appearance of benign tissue several years after such treatment has not been(More)
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