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The findings and conclusions of this paper are not subject to detailed review and do not necessarily reflect the official views and policies of the Lincoln Institute of Land Policy. After printing your initial complimentary copy, please do not reproduce this paper in any form without permission of the authors. Contact the authors directly with all questions(More)
The paper will present results of the NETFRAME project (GRD1-2001-40435): " establishing a documented framework for on-line concurrent engineering and cooperation between large industrial auto and aeronautical companies and its suppliers ". Within the scope of the EU funded GROWTH-project a comprehensive set of methods and tools is developed to support the(More)
OBJECTIVES The aim of our study was to evaluate the diagnostic accuracy of multislice computed tomography (MSCT) coronary angiography using a new 64-slice scanner. BACKGROUND The new 64-slice MSCT scanner has improved spatial resolution of 0.4 mm and a faster rotation time (330 ms) compared to prior MSCT scanners. METHODS We studied 70 consecutive(More)
H igh-density lipoprotein (HDL) has been proposed to have several antiatherosclerotic properties, including the ability to mediate macrophage cholesterol efflux, antioxidant capacity, antiinflammatory properties, nitric oxide–promot-ing activity, and ability to transport proteins with their own intrinsic biological activities. 1 HDL particles are critical(More)
BACKGROUND Whereas acute coronary syndromes (ACS) typically develop from the rupture of lipid core plaque (LCP), lesions causing stable angina are believed to be composed of fibrocalcific plaque. In this study, intracoronary near-infrared spectroscopy (NIRS) was used to determine the frequency of LCP at target and remote sites in patients with ACS versus(More)
BACKGROUND Percutaneous coronary intervention (PCI) is associated with periprocedural myocardial infarction (MI) in 3% to 15% of cases (depending on the definition used). In many cases, these MIs result from distal embolization of lipid-core plaque (LCP) constituents. Prospective identification of LCP with catheter-based near-infrared spectroscopy (NIRS)(More)
Organizations are increasingly turning to outsourcing for software development, in part, to control cost and lower the likelihood of project failure. However, application outsourcing is not without risk. Milestones coupled with gateway reviews are a common mechanism for controlling these risks. Yet, the benefit of milestones must be assessed in light of(More)
Despite significant research progress on the problem of managing systems development risk, we are yet to see this problem addressed from an economic optimization perspective. Doing so entails answering the question: What mitigations should be planned and deployed throughout the life of a systems development project in order to control risk and maximize(More)
OBJECTIVES This study sought to compare the safety, diagnostic efficacy, and efficiency of multi-slice computed tomography (MSCT) with standard diagnostic evaluation of low-risk acute chest pain patients. BACKGROUND Over 1 million patients have emergency center evaluations for acute chest pain annually, at an estimated diagnostic cost of over $10 billion.(More)