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The results of facial surgery are intuitively judged in terms of the visible changes in facial features or proportions. However, describing these morphologic outcomes objectively remains a challenge. Biometric morphing addresses this issue by merging statistical shape analysis and image processing. This study describes the implementation of biometric(More)
A pulse-height spectroscopic technique is used to measure the linear attenuation coefficients of commercially available composite phantom materials designed to simulate the attenuation characteristics of breast fat and breast glandular tissue. The manufacturers have specified the composition of these materials with the goal of matching the linear(More)
PURPOSE To assess a schema for estimating the risk of radiation-induced breast cancer following exposure of the breast to ionizing radiation as would occur with mammography and to provide data that can be used to estimate the potential number of breast cancers, cancer deaths, and woman-years of life lost attributable to radiation exposure delivered(More)
PURPOSE To compare physical measures pertaining to image quality among digital mammography systems utilized in a large breast screening program. To examine qualitatively differences in these measures and differences in clinical cancer detection rates between CR and DR among sites within that program. METHODS As part of the routine quality assurance(More)
Digital breast tomosynthesis uses a limited number (typically 10-20) of low-dose x-ray projections to produce a pseudo-three-dimensional volume tomographic reconstruction of the breast. The purpose of this investigation was to characterize and evaluate the effect of scattered radiation on the image quality for breast tomosynthesis. In a simulation, scatter(More)
Direct conversion detectors offer the potential for very high resolution and high quantum efficiency for x-ray imaging, however, variations in signal can arise due to incomplete charge collection. A charge transport model was developed to describe the signal and noise resulting from incomplete charge collection. This signal to noise ratio (SNR) reduction(More)
A new high-resolution detector has been developed for use in a slot-scanned digital mammography system. The detector is a hybrid device that consists of a CCD operating in time-delay integration mode that is bonded to a 150-microm-thick CdZnTe photoconductor array. The CCD was designed with a detector element pitch of 50 microm. Two devices were evaluated(More)
The art, science, and technology of mammography have developed steadily over the past 35 y. Mammography is a central tool for diagnosis of symptoms of breast cancer. In addition, periodic screening of asymptomatic women in certain age groups has been clearly demonstrated to contribute to reduction of mortality from breast cancer. Technical improvements have(More)
Prophylactic nipple-areolar complex (NAC)-sparing mastectomy (NSM) in BRCA1/2 mutation carriers is controversial over concern regarding residual fibroglandular tissue (FGT) with malignant potential. The objective of this study was to model the volume of FGT in the NAC at a standard retroareolar margin (5 mm) and examine the change in this amount with a(More)