James E. Powell

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Historically, the identification of bacterial or yeast isolates has been based on phenotypic characteristics such as growth on defined media, colony morphology, Gram stain, and various biochemical reactions, with significant delay in diagnosis. Clinical microbiology as a medical specialty has embraced advances in molecular technology for rapid species(More)
Mumps is a contagious vaccine-preventable viral disease that is experiencing a revival in students attending second and third level colleges. Large mumps outbreaks have been reported in several countries despite the presence of childhood immunisation programmes over many years, including measles, mumps, and rubella (MMR) vaccination. In 2008, 1,377 cases of(More)
Received 23 September 2013 Accepted 30 January 2014 Graduate Entry Medical School and Centre for Interventions in Infection, Inflammation & Immunity (4i), University of Limerick, Limerick, Ireland University Hospital Limerick, Dooradoyle, Limerick, Ireland Tallaght Hospital, CFAI Reference Laboratory, Dublin, Ireland Trinity College Dublin, Clinical(More)
OBJECTIVES To describe an outbreak of KPC-2-producing Klebsiella pneumoniae with inter-hospital spread and measures taken to control transmission. METHODS Between January and March 2011, 13 K. pneumoniae isolates were collected from nine patients at hospital A and two patients at hospital B. Meropenem, imipenem and ertapenem MICs were determined by Etest,(More)
OBJECTIVES To estimate the prevalence of chlamydia infection in young men in the Mid-Western Health Board Region of Ireland, and to determine risk factors for its acquisition. METHODS Consecutive men attending orthopaedic clinics (OPD), and a university sports arena (UL) were recruited to a chlamydia prevalence study. All men aged 17-35 who had been(More)
A major stumbling block preventing machines from understanding text is the problem of entity disambiguation. While humans find it easy to determine that a person named in one story is the same person referenced in a second story, machines rely heavily on crude heuristics such as string matching and stemming to make guesses as to whether nouns are(More)
AIM To report the first Irish outbreak of cfr-mediated linezolid-resistant Staphylococcus epidermidis. METHODS Linezolid-resistant S. epidermidis isolated at University Hospital Limerick from four blood cultures, one wound and four screening swabs (from nine patients) between April and June 2013 were characterized by pulsed-field gel electrophoresis(More)
Requirements phase acts as a foundation stone for ensuring the success of any software development process. Over the year, researchers have proposed various techniques/tools for the different activities of the requirements phase of SDLC, but at the same time, there are certainly new research questions and issues too. One of the prominent issues is the(More)
BACKGROUND Carbapenemase-producing Enterobacteriaceae (CPE) may cause healthcare-associated infections with high mortality rates. New Delhi metallo-β-lactamase-1 (NDM-1) is among the most recently discovered carbapenemases. AIM To report the first outbreak of NDM-1 CPE in Ireland, including microbiological and epidemiological characteristics, and(More)
BACKGROUND Escherichia coli (E. coli) comprise part of the normal vaginal microflora. Transfer from mother to neonate can occur during delivery resulting, sometimes, in neonatal bacterial disease. Here, we aim to report the first outbreak of CTX-M ESBL-producing E. coli with evidence of mother-to-neonate transmission in an Irish neonatal intensive care unit(More)