James E. Gentile

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Mosquitoes exhibit 24 hr rhythms in flight activity, feeding, reproduction and development. To better understand the molecular basis for these rhythms in the nocturnal malaria vector Anopheles gambiae, we have utilized microarray analysis on time-of-day specific collections of mosquitoes over 48 hr to explore the coregulation of gene expression rhythms by(More)
Agent-based models (ABMs) have been used to model the behaviour of individual mosquitoes and other aspects of malaria. In this paper, a conceptual entomological model of the population dynamics of Anopheles gambiae and the agent-based implementations derived from it are described. Hypothetical vector control interventions (HVCIs) are implemented to target(More)
Iris recognition has gained popularity due to factors such as its perceived high accuracy, significant usability advantages attributed to its non-contact acquisition method, and the availability of low cost sensors due to improvements in technology. However, non-contact biometrics authentication systems are vulnerable to different types of attacks than(More)
Verification and validation (V&amp;V) techniques are used in agent-based modeling (ABM) to determine whether the model is an accurate representation of the real system. Docking is a form of V&V that tries to align multiple simulation models. In a previous paper, we described the docking process of an ABM that simulates the life cycle of <i>Anopheles(More)
The 24-h day involves cycles in environmental factors that impact organismal fitness. This is thought to select for organisms to regulate their temporal biology accordingly, through circadian and diel rhythms. In addition to rhythms in abiotic factors (such as light and temperature), biotic factors, including ecological interactions, also follow daily(More)
There is a renewed effort to develop novel malaria control strategies as even well-implemented existing malaria control tools may fail to block transmission in some regions. Currently, transgenic implementations of the sterile insect technique (SIT) such as the release of insects with a dominant lethal, homing endonuclease genes, or flightless mosquitoes(More)
Vector-borne diseases account for 16% of the global infectious disease burden (WHO, 2004). Many of these debilitating and sometimes fatal diseases are transmitted between human hosts by mosquitoes. Mosquito-targeted intervention methods have controlled or eliminated mosquito-borne diseases from many regions of the world but regions of constant transmission(More)