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Employing an interval type-2 fuzzy logic and hesitation index in a Multi Criteria Group Decision Making system for lighting level selection in an intelligent environment A fuzzy-genetic tactical resource planner for workforce allocation
Amyotrophic Lateral Sclerosis (ALS) is a devastating progressive neurodegenerative disease. Disease pathophysiology is complex and not yet fully understood, but is proposed to include the accumulation of misfolded proteins, as aggregates are present in spinal cords from ALS patients and in ALS model organisms. Increasing autophagy is hypothesized to be(More)
It has become standard practice to use the traditional information technologies such as web and email in education. But as the University campus becomes increasingly deployed with interconnected computing technology, we begin to ask how the resulting " iCampus " resource can be used in new and novel ways. This paper builds upon our previous work in the area(More)
Recent research into the role of microRNA (miR) in the immune system has identified the miR-29 family as critical regulators of key processes in adaptive immunity. The miR-29 family consists of four members with shared regulatory capacity, namely miR-29a, miR-29b-1, miR-29b-2 and miR-29c. Being expressed in both T and B cells, as well as the main accessory(More)
The cytokine thymic stromal lymphopoietin (TSLP) drives immature B cell development in vitro and may regulate T helper type 2 responses. Here we analyzed the involvement of TSLP in B cell development in vivo with a doxycycline-inducible, keratin 5-driven transgene encoding TSLP (K5-TSLP). K5-TSLP-transgenic mice given doxycycline showed an influx of(More)
The Java Environment for Distributed Invocation (JEDI) is efficient, dynamic, and easier to use than alternative communication systems for distributed Java objects. Existing state-of-the-art mechanisms for remote method calls on Java objects, such as RMI, require users to perform a complicated series of steps. Furthermore, the compiled static interfaces(More)
The establishment and maintenance of central tolerance depends to a large extent on the ability of medullary thymic epithelial cells to express a variety of tissue-restricted antigens, the so-called promiscuous gene expression (pGE). Autoimmune regulator (Aire) is to date the best characterised transcriptional regulator known to at least partially(More)