James D. Hardy

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Hyperalgesia may be defined as a state of increased intensity of pain sensation induced by either noxious or ordinarily non-noxious stimulation of peripheral tissue. Hyperalgesia occurs in both superficial and deep tissues, in areas with pain thresholds that are normal, lowered or raised (1, 2). As seen at the bedside there are apparently several varieties(More)
For purposes of theoretical analysis of experimental results and evaluation of hypothetical concepts a mathematical model of thermoregulation in man is presented. The human body is represented by three cylinders: the head, the trunk, and the extremities. Each cylinder is divided into two or more concentric layers to represent anatomical and functional(More)
Normal mammary epithelial cells express the cell surface protein biliary glycoprotein (BGP or CD66a) in a polarized manner, suggesting that this protein may play a role in the formation of mammary acini. In order to test this hypothesis, we interrupted the expression of BGP in the mammary epithelial line MCF10F when cultured in or on Matrigel, a source of(More)