James Cruickshanks

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Host species have evolved mechanisms that can inhibit pathogen replication even after a cell has been successfully invaded. Here we show that tripartite-motif protein 21 (TRIM21), a ubiquitously expressed E3 ubiquitin ligase that targets viruses inside the cytosol, protects mice against fatal viral infection. Upon infection with mouse adenovirus-1, naive(More)
The Family of Integrated Rapid Response Equipment (FIRRE) is an advanced technology demonstration program intended to develop a family of affordable, scalable, modular, and logistically supportable unmanned systems to meet urgent operational force-protection needs and requirements worldwide. The near-term goal is to provide the best available unmanned(More)
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