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Tubulin is a major component of the eukaryotic cytoskeleton, controlling cell shape, structure and dynamics, whereas its bacterial homologue FtsZ establishes the cytokinetic ring that constricts during cell division. How such different roles of tubulin and FtsZ evolved is unknown. Studying Archaea may provide clues as these organisms share characteristics(More)
No systems have been reported for genetic manipulation of cold-adapted Archaea. Halorubrum lacusprofundi is an important member of Deep Lake, Antarctica (~10% of the population), and is amendable to laboratory cultivation. Here we report the development of a shuttle-vector and targeted gene-knockout system for this species. To investigate the function of(More)
Oscillations of the Min protein system are involved in the correct midcell placement of the divisome during Escherichia coli cell division. Based on molecular interactions of the Min system, we formulated a mathematical model that reproduces Min patterning during cell growth and division. Specifically, the increase in the residence time of MinD attached to(More)
The influence of ambient fluid stratification on buoyant miscible jets and plumes is studied theoretically and experimentally. Given a fixed set of jet/plume parameters, and an ambient fluid stratification sandwiched between top and bottom homogeneous densities, a theoretical criterion is identified to show how step-like density profiles constitute the most(More)
Over 40 years ago, M. Budyko and W. Sellers independently introduced low-order climate models that continue to play an important role in the mathematical modeling of climate. Each model has one spatial variable, and each was introduced to investigate the role ice-albedo feedback plays in influencing surface temperature. This paper serves in part as a(More)
Dedicated to Paul Blanchard on the occasion of his sixtieth birthday. Abstract: The dynamics of a simple model of three charged bodies interacting under an inverse square electrostatic force is presented. The model may be viewed as an alternative to the pendulum, the standard model of a periodically forced and damped nonlinear oscillator.
Modern fluorescence microscopy requires software-controlled illumination sources with high power across a wide range of wavelengths. Diode lasers meet the power requirements and combining multiple units into a single fiber launch expands their capability across the required spectral range. We present the NicoLase, an open-source diode laser combiner, fiber(More)
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