James C. Reeves

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BACKGROUND Pazopanib and sunitinib provided a progression-free survival benefit, as compared with placebo or interferon, in previous phase 3 studies involving patients with metastatic renal-cell carcinoma. This phase 3, randomized trial compared the efficacy and safety of pazopanib and sunitinib as first-line therapy. METHODS We randomly assigned 1110(More)
The common assertion that scientific plant breeding leads to a narrowing in crop diversity has been examined. We have characterised the dominant UK winter wheat varieties from the period 1934–1994 using two types of PCR-based DNA profiling (AFLPs, amplified fragment length polymorphisms, and SSRs, simple-sequence repeats, microsatellites), seed storage(More)
Genetic-diversity assessments, using both phenotypic and molecular-marker data, were made on a collection of 134 barley varieties (both winter and spring types), chosen on the basis of their representation on the NIAB 'Recommended List' over the period 1925–1995. Genotypic (AFLP and SSR) and phenotypic (UPOV characters) data were analysed to determine(More)
OBJECTIVE Given the growing number of military service members with families and the multiple combat deployments characterizing current war time duties, the impact of deployments on military children requires clarification. Behavioral and emotional adjustment problems were examined in children (aged 6 through 12) of an active duty Army or Marine Corps(More)
The changes of genetic diversity over time were monitored in 504 European barley cultivars released during the 20th century by genotyping with 35 genomic microsatellites. For analysis, the following four temporal groups were distinguished: 1900–1929 (TG1 with 19 cultivars), 1930–1949 (TG2 with 40 cultivars), 1950–1979 (237 cultivars as TG3), and 1980–2000(More)
The use of AFLP analysis to produce DNA profiles from a set of 55 wheat varieties, commonly grown in the UK over the past 60 years, is described. Using six different primer pairs, 90 polymorphic bands were readily recognised and recorded. These AFLP bands are not significantly clustered and hence can be used with some confidence, even though they are not(More)
The barley β-amylase I (Bmy1) locus encodes a starch breakdown enzyme whose kinetic properties and thermostability are critical during malt production. Studies of allelic variation at the Bmy1 locus have shown that the encoded enzyme can be commonly found in at least three distinct thermostability classes and demonstrated the nucleotide sequence variations(More)
Children aged 5-13 years with DSM-III diagnoses of Attention Deficit (ADDH), Anxiety, (ANX), or Conduct plus ADDH (HC) Disorder and matched normal controls were compared on a set of laboratory measures of impulsivity, arousal, motor performance, activity level, and cognition, and on behavior ratings during testing. While ANX patients did not differ from(More)