James B. Mercer

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Cardiovascular diseases (CVD) are responsible for around 20% of all deaths worldwide (approximately 14 million) and are the principal cause of death in all developed countries, accounting for 50% of all deaths. Variations in the annual per capita death rates in different countries are well documented. Less well known are seasonal variations in death rates,(More)
We have investigated how total body thermosensitivity in various mammalian and avian species (mouse, rat, golden hamster, guinea pig, rabbit, dog, goat, pigeon, duck, goose) is related to their respective local thermosensitivities in the hypothalamus, spinal cord and skin. Local and total thermosensitivities were determined by measuring the relationship(More)
Flap failure in free-tissue transfer relates strongly to technical failure of the anastomosis or to kinking as well as to external compression of the donor or recipient vessels. Intraoperative monitoring of flap perfusion has shown to prevent flap failure. This prospective, clinical study presents the results of intraoperative dynamic infrared thermography(More)
BACKGROUND Water-filtered infrared-A (wIRA) is a special form of heat radiation with a high tissue-penetration and with a low thermal burden to the surface of the skin. wIRA is able to improve essential and energetically meaningful factors of wound healing by thermal and non-thermal effects. AIM OF THE STUDY prospective study (primarily planned(More)
The central portion of chronic wounds is often hypoxic and relatively hypothermic, representing a deficient energy supply of the tissue, which impedes wound healing or even makes it impossible. Water-filtered infrared-A (wIRA) is a special form of heat radiation with a high tissue penetration and a low thermal load to the skin surface. wIRA produces a(More)
1. Extrahypothalamic thermosensitivity at normal (39 degrees C) and lowered (33.8 degrees C) hypothalamic clamp temperatures has been measured in cold exposed rabbits equipped with chronically implanted hypothalamic perfusion thermodes. The animals were subjected to body core cooling by means of cold perfused thermodes placed in the colon. 2. At lowered(More)
Shivering threshold and thermosensitivity were determined in six conscious rabbits at ambient temperature (Ta) 20 and 10 degrees C before and at six different times after saline injection (0.15 ml iv) and polyriboinosinic-polyribocytidylic acid (poly I:C)-induced fever (5 micrograms/kg iv). Thermosensitivity was calculated by regression of metabolic heat(More)
The threshold body core temperature for selective brain cooling (SBC) as well as the slope of brain cooling were determined in three Norwegian reindeer (Rangifer tarandus tarandus) during rest and during exercise. Brain temperature was measured in the hypothalamus (Thypo) and blood temperature (Tblood) was measured either in the right carotid artery or in a(More)