James A. Hanley

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The meaning and use of the area under a receiver operating characteristic (ROC) curve.

A representation and interpretation of the area under a receiver operating characteristic (ROC) curve obtained by the "rating" method, or by mathematical predictions based on patient characteristics,… (More)

A method of comparing the areas under receiver operating characteristic curves derived from the same cases.

Receiver operating characteristic (ROC) curves are used to describe and compare the performance of diagnostic technology and diagnostic algorithms. This paper refines the statistical comparison of… (More)

Adverse events associated with prescription drug cost-sharing among poor and elderly persons.

Robyn Tamblyn, Réjean Laprise, +11 authors Luc Mallet
JAMA
2001

CONTEXT Rising costs of medications and inequities in access have sparked calls for drug policy reform in the United States and Canada. Control of drug expenditures by prescription cost-sharing for… (More)

Statistical practice in high-throughput screening data analysis

Nathalie Malo, James A. Hanley, S Cerquozzi, J. -P. Pelletier, Robert Nadon
Nature Biotechnology
2006

High-throughput screening is an early critical step in drug discovery. Its aim is to screen a large number of diverse chemical compounds to identify candidate 'hits' rapidly and accurately. Few… (More)

Receiver operating characteristic (ROC) methodology: the state of the art.

James A. Hanley
Critical reviews in diagnostic imaging
1989

Receiver operating characteristic (ROC) methodology has been increasingly used in medical applications in the last 10 years. The text by Swets and Pickett has popularized the technique and the… (More)

Statistical analysis of correlated data using generalized estimating equations: an orientation.

James A. Hanley, Abdissa Negassa, Michael D deB Edwardes, Janet Forrester
American journal of epidemiology
2003

The method of generalized estimating equations (GEE) is often used to analyze longitudinal and other correlated response data, particularly if responses are binary. However, few descriptions of the… (More)

Statistical approaches to the analysis of receiver operating characteristic (ROC) curves.

Barbara J Mcneil, James A. Hanley
Medical decision making : an international…
1984

In this article we review published and some unpublished work in statistical analyses of ROC curves. We describe both single and joint indices and indicate the approaches that have been taken to… (More)

Prostate cancer and the Will Rogers phenomenon.

Peter C Albertsen, James A. Hanley, +4 authors Judith Fine
Journal of the National Cancer Institute
2005

BACKGROUND Information on tumor stage and grade are used to assess cancer prognosis and to produce standardized comparisons of end results over time. Changes in the interpretation of classification… (More)

Insulin resistance syndrome in a representative sample of children and adolescents from Quebec, Canada

Marie Lambert, Gilles Paradis, Jennifer O'loughlin, Edgard E. Delvin, James A. Hanley, Émile Lévy
International Journal of Obesity
2004

OBJECTIVES: To estimate the prevalence of insulin resistance syndrome (IRS) in a representative sample of youth. To test for the independent contribution of insulin resistance (IR) and adiposity to… (More)

Streptozocin Alone Compared with Streptozocin plus Fluorouracil in the Treatment of Advanced Islet-Cell Carcinoma

Charles G. Moertel, James A. Hanley, L. Audrey Johnson
The New England journal of medicine
1980

To evaluate the treatment of advanced islet-cell carcinoma, we randomly assigned 84 patients to streptozocin alone or streptozocin plus fluorouracil. Each regimen was given in five-day courses. The… (More)

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