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Journals and Conferences
Contributing Authors R. Betts, R. Charlson, C. Chuang, J.S. Daniel, A. Del Genio, R. van Dorland, J. Feichter, J. Fuglestvedt, P.M. de F. Forster, S.J. Ghan, A. Jones, J.T. Kiehl, D. Koch, C. Land, J. Lean, U. Lohmann, K. Minschwaner, J.E. Penner, D.L. Roberts, H. Rodhe, G.J. Roelofs, L.D. Rotstayn, T.L. Schneider, U. Schumann, S.E. Schwartz, M.D.… (More)
Xylem from stems of genetically manipulated tobacco plants which had had cinnamyl alcohol dehydrogenase (CAD; EC 18.104.22.168) activity down-regulated to a greater or lesser degree (clones 37 and 49, respectively) by the insertion of antisense CAD cDNA had similar, or slightly higher, lignin contents than xylem from wild-type plants. Fourier-transform infrared… (More)
The optimal overlap between two molecular structures is a useful measure of shape similarity. However, it usually requires significant computation. This work describes the design of shape-fingerprints: binary bit strings that encode molecular shape. Standard measures of similarity between two shape-fingerprints are shown to be an excellent surrogate for… (More)
The eight contributions here provide ample evidence that shape as a volume or as a surface is a vibrant and useful concept when applied to drug discovery. It provides a reliable scaffold for "decoration" with chemical intuition (or bias) for virtual screening and lead optimization but also has its unadorned uses, as in library design, ligand fitting, pose… (More)
This paper reviews algorithms which rely on the analysis of time domain samples to provide energy and zero-crossing rates, together with more recent algorithms that use diierent methods for speech detection. We then examine a diierent approach using cepstral analysis, showing a high degree of amplitude and noise level independence. We show that a cepstral… (More)
We apply a recently published method of text-based molecular similarity searching (LINGO) to standard data sets for the purpose of quantifying the accuracy of the approach. Our implementation is based on a pattern-matching finite state machine (FSM) which results in fast search times. The accuracy of LINGO is demonstrated to be comparable to that of a… (More)
DNA microsatellites originally detected in sheep and cattle are also detectable in North American elk (Wapiti) using polymerase chain reactions. We have developed a parentage test in elk using eleven microsatellite markers that are highly polymorphic and informative.
2-Acetoxy-4′-chlor-3,5-dijodbenzanilid zeigte eine hohe Wirksamkeit gegen junge und gereifteF. hepatica andH. controtus in Schaften bei einer oralen Dosis von 25 und 40 mg/kg. Die gute Verträglichkeit der Verbindung in Schafen ergab sich aus Feldversuchen in Australien.