James A. Covington

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There are currently no practical systems that allow extended regions (>5 mm(2)) of a tissue slice in vitro to be exposed, in isolation, to changes in ionic conditions or to pharmacological manipulation. Previous work has only achieved this at the expense of access to the tissue for recording electrodes. Here, we present a chamber that allows a tissue slice(More)
BACKGROUND The pathogenesis of inflammatory bowel disease (IBD) involves the role of bacteria. These bacteria ferment nonstarch polysaccharides in the colon producing a fermentation profile that through altered gut permeability can be traced in urine. We proposed to track the resultant volatile organic compounds or gases that emanate from urine using(More)
— In this paper, we present the analog circuit design and implementation of an adaptive neuromorphic olfaction chip. An analog VLSI device with on-chip chemosensor array, on-chip sensor interface circuitry and on-chip learning neuromorphic olfactory model has been fabricated in a single chip using Austria Microsystems 0.6 µm CMOS technology. Drawing(More)
Smell is a key human sense which can significantly effect our perception of an environment. Although, typically not as developed as our other senses, the presence of a pleasant or unpleasant smell can alter the way we view a scene. Such a cross-modal effect can be substantial with parts of a scene literally going unnoticed as the smell dominates our senses.(More)
A novel method for the production of inhibitor- and solvent-free resins suitable for three-dimensional (3D) microstereolithography is reported. Using an exemplar poly(ethylene glycol)-based resin, the control of features in the X, Y, and Z planes is demonstrated such that complex structures can be manufactured. Human mesenchymal stem cells cultured on the(More)
  • Jim R Adams, Emily Ward, Stephen A Covington, James A, Amandip S Sahota, Ravi Gowda +8 others
  • 2016
(2016) A simple breath test for tuberculosis using ion mobility : a pilot study. Tuberculosis, 99. pp. 143-146. Copyright and reuse: The Warwick Research Archive Portal (WRAP) makes this work of researchers of the University of Warwick available open access under the following conditions. This article is made available under the Creative Commons Attribution(More)
This paper describes our efforts to implement the world's first silicon olfactory system in aVLSI/MEMs. To achieve this requires integration of a biologically constained neuronal model, chemical micro-sensor technology and aVLSI spiking neuromorphic circuits. Here we describe our progress towards this goal, by presenting an olfactory bulb model, a reduced(More)
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