James A. Bentley

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A molecular descriptor space has been developed which describes structural diversity. Large databases of molecules have been mapped into it and compared. This analysis used five chemical databases, CMC and MDDR, which represent knowledge bases containing active medicinal agents, ACD and SPECS, two databases of commercially available compounds, and finally(More)
With the recent advent of cervical cancer vaccines, many questions relating to the best overall prevention methods for cervical disease are beginning to arise. A Markov model was used across five geographic regions (Canada, The Netherlands, Taiwan, UK, US) to examine the clinical benefits and cost-effectiveness of: (1) vaccination combined with screening,(More)
Genetic parameters for meat quality traits and their relationships with body weight and breast development were estimated for a total of 420 male turkeys using REML. The birds were slaughtered in a commercial plant and the traits measured included pH at 20 min (pH20) and 24 h post-mortem (pHu) and colour of the breast and thigh meat. The heritabilities of(More)
PURPOSE  To determine the long-term oncologic outcomes and toxicity of patients treated with definitive chemo-radiotherapy for cervical cancer.  METHODS AND MATERIALS  The study period was January 1, 2000 to December 31, 2009. All patients diagnosed with cervical cancer who received curative-intent chemoradiotherapy were included. Patients were excluded(More)
Background: Cervical cancer is the third most common cancer in the world, with 2.3 million prevalent cases and 510,000 incident cases documented each year. Annually, 288,000 women die of cervical cancer, and 80% of these deaths occur in developing countries. The population of Saudi Arabia is young and growing at an increasing rate. The estimated number of(More)
  • Tony G Johnson, Tim O Adams, Anne Jenkins, Janet Griffin, Sharon Johnson, Charlene Walker +4 others
  • 2009
i Foreword This report contains the findings of a 2007 canvass of all primary wood-using plants in South Carolina, and presents changes in product output and residue use since 2005. It complements the Forest Inventory and Analysis (FIA) periodic inventory of volume and removals from the State's timberland. The canvass was conducted to determine the amount(More)
Blood cultures are an important investigation to help tailor effective management for patients with severe sepsis. Frequent contaminated samples increase laboratory workload and can delay or cause incorrect changes to patient management. This can prolong patient hospitalisation, increase the risk of harm and increase cost to health boards. Current(More)
BACKGROUND Patients with platinum-sensitive recurrent ovarian cancer are a heterogeneous group, and it is not possible to accurately predict the progression-free survival (PFS) in these patients. We developed and validated a nomogram to help improve prediction of PFS in patients treated with platinum-based chemotherapy. METHODS The nomogram was developed(More)
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