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Increases in energy, lipid and carbohydrate intakes during the luteal phase have been previously observed. However, it is not known whether this is due to phase-dependent variations in the reward value of certain foods. Moreover, increases in olfactory sensitivity have been proposed and may be involved in these changes in food reward. Therefore, we examined(More)
INTRODUCTION We examined the impact of a 24 hour complete fast (vs. fed state) on two measures of food reward: 1) 'wanting', as measured by response to food images and by the relative-reinforcing value of food (RRV), and 2) 'liking', as measured by response to food images and the hedonic evaluation of foods consumed. METHODS Utilizing a randomized(More)
Evidence suggests that when animals are chronically deprived of calories, the reward of a food stimulus becomes more salient. Recently leptin has been implicated in food reward. The objective of this study was to examine the effect of weight-loss on food hedonics and on the reinforcing value of palatable snack food, and to determine whether plasma leptin(More)
Traditionally there has been a tendency to focus on peripheral "bottom-up" feeding-related signals and their resulting downstream actions on hypothalamic centers when studying the feeding behaviour of animals. A problem with this hierarchal approach emerges especially with respect to acquiring a human model attempting to explain what is ultimately a(More)
Changes in smell function can modify feeding behaviour but there is little evidence of how acute negative energy balance may impact olfaction and palatability. In a within-subjects repeated measures design, 15 subjects (nine male; six female) aged 28.6±4.5 years with initial body weight (BW) 74.7±4.9 kg and body mass index (BMI) 25.3±1.4 kg/m(2) were(More)
INTRODUCTION Polymorphisms of the dopamine receptor D2 (DRD2) gene have been associated with obesity phenotypes. Our aim was to examine if the genotype of TaqIA Restriction Fragment Length Polymorphism (RFPL) was related to an attenuated weight loss response or to changes in energy expenditure (EE) and food preference before and after weight loss. methods:(More)
In this study we describe the molecular and cellular characterization of a zebrafish mutant that develops tumors in the optic pathway. Heterozygous Tg(flk1:RFP)is18 transgenic adults develop tumors of the retina, optic nerve and optic tract. Molecular and genetic mapping demonstrate the tumor phenotype is linked to a high copy number transgene array(More)
In a recent issue of this journal, Lamboglia and colleagues published a review paper entitled " Exergaming as a strategic tool in the fight against childhood obesity: a systematic review " [1]. The rationale for this review was that physical activity levels among children and adolescents are very low, and time spent in sedentary behaviors, especially screen(More)
OBJECTIVE To determine the effects of aerobic training, resistance training, and combined training on mood, body image, and self-esteem in adolescents with obesity. METHOD After a 4-week prerandomization treatment, 304 postpubertal adolescents (91 males, 213 females) with obesity ages 14-18 years were randomized to 1 of 4 groups for 22 weeks: aerobic(More)
Adolescents spend up to 6-8 h/day in sedentary screen behaviour and screen time is an independent risk factor for obesity. However, the mechanisms by which screen time confers obesity risk remain unclear. Via community level recruitment this study examined whether the relationship between screen time behaviours and body mass index (BMI: kg/m2) was mediated(More)