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  • Jakyung Yoo, Joo Hee Kim, Keith D. Robertson, José L. Medina-Franco
  • Biology, Chemistry, Medicine
  • Advances in protein chemistry and structural…
  • 2012
  • DNA methyltransferases (DNMTs) are promising epigenetic targets for the development of novel anticancer drugs and other diseases. Molecular modeling and experimental approaches are being used toContinue Reading
  • Jianing Wang, Uma S Singh, +10 authors Chung K Chu
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2011 (First Published: 1 November 2011)
  • Novel 2'-fluoro-6'-methylene-carbocyclic adenosine (9) was synthesized and evaluated its anti-HBV activity. The titled compound demonstrated significant antiviral activity against wild-type as wellContinue Reading
  • Ja-Hwan Seol, Hye-Jin Kim, Jakyung Yoo, Hyun-Ju Park, Eun-Jung Cho
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 2008 (First Published: 1 September 2008)
  • To understand the role of histone H3 sub-domains in chromatin function, 35 histone H3 tandem alanine mutants were generated and tested for their viability and sensitivity to DNA damaging agents.Continue Reading