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The ionic current responsible for terminating the action potential (AP), and thereby in part determining the AP duration (APD), is the potassium current (IK), consisting of primarily two components:(More)
Cultured astrocytes treated with siRNA to knock down glutamate dehydrogenase (GDH) were used to investigate whether this enzyme is important for the utilization of glutamate as an energy substrate.(More)
Alterations in brain energy metabolism have been suggested to be of fundamental importance for the development of Alzheimer’s disease (AD). However, specific changes in brain energetics in the early(More)