Jaime Hernández

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OBJECTIVE To evaluate the efficacy and safety profile of one 30-mg nimodipine oral tablet taken three times per day (one tablet with breakfast, one with lunch, and one with dinner) or one 150-mg cinnarizine verum oral capsule taken once each day with dinner for 12 weeks. STUDY DESIGN Comparative in a double-blind, multinational pilot study. SETTING(More)
Bradykinesia is a frequent finding in Huntington's disease (HD), but some aspects are presently unknown; including the natural evolution of bradykinesia over time and the correlation between bradykinesia and functional capacity. We studied the motor performance of 20 genetically confirmed patients with HD (age: 40+/-10.8 years; age at onset 33.6+/-11 years;(More)
BACKGROUND Chagas disease is caused by the protozoan Trypanosoma cruzi, which is transmitted to mammal hosts by triatomine insect vectors. The goal of this study was to model the spatial distribution of triatomine species in an endemic area. METHODS Vector's locations were obtained with a rural householders' survey. This information was combined with(More)
  • Joachim Maack, Teja Kattenborn, Fabian Ewald Fassnacht, Fabian Enßle, Jaime Hernández, Patricio Corvalán +1 other
  • 2015
We used spectral, textural and photogrammetric information from very-high resolution (VHR) stereo satellite data (Pléiades and WorldView-2) to estimate forest biomass across two test sites located in Chile and Germany. We compared Random Forest model performances of different predictor sets (spectral, textural, and photogrammetric), forest inventory designs(More)
ColE1 plasmid replication is unidirectional and requires two DNA polymerases: DNA polymerase I (Pol I) and DNA polymerase III (Pol III). Pol I initiates leading-strand synthesis by extending an RNA primer, allowing the Pol III holoenzyme to assemble and finish replication of both strands. The goal of the present work is to study the interplay between Pol I(More)
Disentangling the contribution of corridors to landscape connectivity is crucial for adopting efficient measures in conservation, but their actual role in heterogeneous landscapes is not yet fully understood. We assessed the hypothesis that corridors, consisting of hedgerows and riparian vegetation strips, are important landscape elements promoting(More)
Regionalized variables with discrete distributions are commonly associated with counts of individuals (precious stones in ore deposits, wild animals in ecosystems, trees in forests, etc.), that can be represented by a spatial point process. In this paper, we propose to model the point distribution by a Cox process, i.e., a Poisson point process with a(More)
In this paper we present a hybrid path-following algorithm that generates inexact Newton steps suited for solving large scale and/or degenerate nonlinear programs. The algorithm uses as a central region a relaxed notion of the central path, called quasicentral path, a generalized augmented Lagrangian function, weighted proximity measures, and a linesearch(More)
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