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  • Flávia L Osório, Rafael Faria Sanches, +7 authors Jaime E. C. Hallak
  • Psychology, Medicine
  • Revista brasileira de psiquiatria
  • 2015 (First Published: 1 March 2015)
  • OBJECTIVES Ayahuasca (AYA), a natural psychedelic brew prepared from Amazonian plants and rich in dimethyltryptamine (DMT) and harmine, causes effects of subjective well-being and may therefore haveContinue Reading
  • Jaime E. C. Hallak, Joao Paulo Maia-de-Oliveira, +6 authors Serdar M. Dursun
  • Medicine
  • JAMA psychiatry
  • 2013 (First Published: 1 July 2013)
  • IMPORTANCE The treatment of schizophrenia remains a challenge, and the currently available antipsychotic drugs are slow acting and produce a number of adverse effects. OBJECTIVE To examine theContinue Reading
  • Jaime E. C. Hallak, João Paulo Machado-de-Sousa, +6 authors Antonio Waldo Zuardi
  • Psychology, Medicine
  • Revista brasileira de psiquiatria
  • 2010 (First Published: 1 March 2010)
  • OBJECTIVE The last decade has seen increasing evidence of dysfunctions in the endogenous cannabinoid system in schizophrenia and of its relationship with the typical cognitive impairment of theContinue Reading
  • Marcos Hortes Nisihara Chagas, Antonio Waldo Zuardi, +7 authors José Alexandre S. Crippa
  • Psychology, Medicine
  • Journal of psychopharmacology
  • 2014 (First Published: 1 November 2014)
  • Introduction: Parkinson’s disease (PD) has a progressive course and is characterized by the degeneration of dopaminergic neurons. Although no neuroprotective treatments for PD have been found toContinue Reading
  • Rafael Guimarães Dos Santos, Flávia L Osório, José Alexandre S. Crippa, Jordi Riba, Antonio Waldo Zuardi, Jaime E. C. Hallak
  • Psychology, Medicine
  • Therapeutic advances in psychopharmacology
  • 2016 (First Published: 1 June 2016)
  • To date, pharmacological treatments for mood and anxiety disorders and for drug dependence show limited efficacy, leaving a large number of patients suffering severe and persistent symptoms.Continue Reading
  • Rafael Guimarães Dos Santos, Flávia L Osório, José Alexandre S. Crippa, Jaime E. C. Hallak
  • Psychology, Medicine
  • Revista brasileira de psiquiatria
  • 2016 (First Published: 1 March 2016)
  • OBJECTIVE To conduct a systematic literature review of animal and human studies reporting anxiolytic or antidepressive effects of ayahuasca or some of its isolated alkaloids (dimethyltryptamine,Continue Reading
  • Samira S Valvassori, Daniela Vicente Bavaresco, +7 authors João Quevedo
  • Medicine
  • Revista brasileira de psiquiatria
  • 2013 (First Published: 1 December 2013)
  • OBJECTIVE To investigate the effects of cannabidiol (CBD) on mitochondrial complex and creatine kinase (CK) activity in the rat brain using spectrophotometry. METHOD Male adult Wistar rats wereContinue Reading
    Recently, the anti-addictive potential of ayahuasca, a dimethyltryptamine(DMT)- and β-carboline-rich hallucinogenic beverage traditionally used by indigenous groups of the Northwest Amazon andContinue Reading
  • Flávia de Lima Osório, Sonia R. Loureiro, +15 authors José Alexandre S. Crippa
  • Psychology, Medicine
  • Psychiatry and clinical neurosciences
  • 2019 (First Published: 14 October 2019)
  • AIM The Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders is one of the most used diagnostic instruments in clinical research worldwide. The current versionContinue Reading