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We report here on a 250-GHz electron spin resonance (ESR) study of macroscopically aligned model membranes composed of mixtures of dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylserine (DMPS), utilizing the nixtroxide-labeled cholesterol analog cholestane (CSL). Two clearly resolved spectral components, distinct in both their ordering and(More)
OBJECTIVE Patients with rheumatoid arthritis (RA) commonly switch between tumor necrosis factor (TNF) inhibitors after failing to control disease activity. Much of the clinical data that support switching to a second TNF agent when one agent fails to work has come from small, short-term studies. We utilized a US insurance claims database to determine(More)
Electron spin resonance (ESR) spectroscopy at 250 GHz and 9 GHz is utilized to study the dynamics and local structural ordering of a nitroxide-labeled enzyme, T4 lysozyme (EC, in aqueous solution from 10 degrees C to 35 degrees C. Two separate derivatives, labeled at sites 44 and 69, were analyzed. The 250-GHz ESR spectra are well described by a(More)
Human movement monitoring using wireless sensors has become an important area of research today. The use of wireless sensors in human identification is a relatively new idea with interesting applications in portable device security and user recognition. In this paper, we describe a real-time wireless sensor system based on inexpensive inertial sensors that(More)
An analysis of an 11 year experience with the routine use of Marlex (polypropylene) mesh reinforcement of the canal floor in both indirect and direct inguinal herniorraphy is presented. All patients in good general health were accepted regardless of their age or weight. Survey responses were obtained from a large and representative sample of this(More)
BACKGROUND Randomized studies have demonstrated improved attainment of target low-density lipoprotein cholesterol (LDL-C) values when ezetimibe is combined with statins for the treatment of hypercholesterolemia. However, the efficacy of an intervention in randomized controlled clinical studies may not correlate with its efficacy in a real-world (community(More)
Receptor-linked tyrosine phosphatases regulate cell growth by dephosphorylating proteins involved in tyrosine kinase signal transduction. Within this gene family, the leukocyte common antigen-related (LAR) gene is of particular interest with respect to the nervous system because it has sequence similarity to the neural cell adhesion molecule N-CAM and is(More)
Monitoring human activities using wearable wireless sensor nodes has the potential to enable many useful applications for everyday situations. The deployment of a compact and computationally efficient grammatical representation of actions reduces the complexities involved in the detection and recognition of human behaviors in a distributed system. In this(More)