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We report here on a 250-GHz electron spin resonance (ESR) study of macroscopically aligned model membranes composed of mixtures of dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylserine (DMPS), utilizing the nixtroxide-labeled cholesterol analog cholestane (CSL). Two clearly resolved spectral components, distinct in both their ordering and(More)
Electron spin resonance (ESR) spectroscopy at 250 GHz and 9 GHz is utilized to study the dynamics and local structural ordering of a nitroxide-labeled enzyme, T4 lysozyme (EC, in aqueous solution from 10 degrees C to 35 degrees C. Two separate derivatives, labeled at sites 44 and 69, were analyzed. The 250-GHz ESR spectra are well described by a(More)
OBJECTIVE Patients with rheumatoid arthritis (RA) commonly switch between tumor necrosis factor (TNF) inhibitors after failing to control disease activity. Much of the clinical data that support switching to a second TNF agent when one agent fails to work has come from small, short-term studies. We utilized a US insurance claims database to determine(More)
Human movement monitoring using wireless sensors has become an important area of research today. The use of wireless sensors in human identification is a relatively new idea with interesting applications in portable device security and user recognition. In this paper, we describe a real-time wireless sensor system based on inexpensive inertial sensors that(More)
Receptor-linked tyrosine phosphatases regulate cell growth by dephosphorylating proteins involved in tyrosine kinase signal transduction. Within this gene family, the leukocyte common antigen-related (LAR) gene is of particular interest with respect to the nervous system because it has sequence similarity to the neural cell adhesion molecule N-CAM and is(More)
Monitoring human activities using wearable wireless sensor nodes has the potential to enable many useful applications for everyday situations. The deployment of a compact and computationally efficient grammatical representation of actions reduces the complexities involved in the detection and recognition of human behaviors in a distributed system. In this(More)
Research indicates that various disorders in aging ranging from mild cognitive impairment to dementia and Alzheimer's could be diagnosed early based on the study of locomotion. Sensor platforms integrated into clothing provide the possibility of reliable locomotion monitoring. In this work, we describe a system using inexpensive, off-the-shelf inertial(More)