Jagtar Singh

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A novel strain of Bacillus sphaericus JS1 producing thermostable alkaline carboxymethyl cellulase (CMCase; endo-1,4-β-glucanase, E.C. 3.2.1.4) was isolated from soil using Horikoshi medium at pH 9.5. CMCase was purified 192-fold by (NH4)2SO4 precipitation, ion exchange and gel filtration chromatography, with an overall recovery of 23%. The CMCase is a(More)
A series of experiments was conducted on the rehabilitation of mine spoil in a dry tropical region of India for determining the suitability of tree species for plantation, growth performance of selected indigenous species in monoculture and impact of the plantations on the restoration of biological fertility of soil. All of the 17 indigenous species(More)
A strain of Bacillus coagulans RCS3 isolated from a hot-water spring produced significant beta-galactosidase activity at 10 days of growth in a flask. While enzyme production was maximum at 50 degrees C, the highest activity was at 65 degrees C, where the half-life was 2 h. A 2 degrees C decrease in temperature increased the half-life to 15 h without(More)
Adherence to the prescribed anti-tuberculosis drug (ATD) treatment is crucial for curing patients with active TB. Anti-tuberculosis drug (ATD) induced hepatotoxicity (ATDH) may contribute to ATD's poor compliance in patients with tuberculosis (TB) as interruption of treatment and the switch to second-line anti-tuberculosis drugs, which is required in(More)
According to the National Family Health Survey, asthma is one of the leading diseases in India. In order to understand the complexity of asthma, the susceptibility genes need to be targeted for their association. Glutathione S-transferases play a major role in the detoxification of metabolites of oxidative stress resulting in inflammation and asthma. In the(More)
BACKGROUND Asthma is the most prevalent disease in India according to the national survey conducted by NFHS 2 in 1998-399. Prostaglandin D2 (PGD2) is a bronchoconstriction inducing metabolite of arachidonic acid in the mast cells, which is produced on exposure to allergens and acts as a ligand for the Prostaglandin D2 Receptor (PTGDR). Polymorphisms in the(More)
BACKGROUND IL-18, a pleiotropic, pro-inflammatory cytokine that plays a major role in innate as well as acquired immunity, has been implicated in asthma etiology and this is the first study investigating the role of IL-18 -137G/C (rs 187238) promoter polymorphism in asthma pathogenesis in a North Indian population. METHODS A pilot study was conducted with(More)
This paper will review all the Total Productive Maintenance (TPM) Pillars, TPM Implementation methodology and the contribution of TPM towards improving manufacturing performance.. It will also focus on calculating the Overall Equipment Effectiveness (OEE) in one of the two wheeler automobile Industry in India. The relationship between various TPM(More)
High-speed steel (HSS) tools are the most commonly used tools in small and medium-scale industry. Cryogenic treatment can be used to enhance the tool life. Studies on cryogenically treated (CT) cutting tools show micro structural changes in the material that can influence the life of the tools significantly. This paper primarily reports performance of CT(More)
Microorganisms constitute two third of the Earth's biological diversity. As many as 99% of the microorganisms present in certain environments cannot be cultured by standard techniques. Culture-independent methods are required to understand the genetic diversity, population structure and ecological roles of the majority of organisms. Metagenomics is the(More)