Jafar Mehvari Habibabadi

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In the present paper a number of techniques were applied to determine the effects of epileptic seizure on spontaneous ongoing EEG. The idea is that seizure represents transitions of an epileptic brain from its normal (chaotic) state to an abnormal (more ordered) state. Some nonlinear measures including correlation dimension, maximum Lyapunov exponent and(More)
Alterations in the balance of K-Na-2Cl cotransporter (NKCC1) and Na-Cl cotransporter (KCC2) activity may cause depolarizing effect of γ-aminobutyric Acid (GABA), and contribute to epileptogenesis in human temporal lobe epilepsy. NKCC1 facilitates accumulation of chloride inside neurons and favors depolarizing responses to GABA. In the current pilot study we(More)
BACKGROUND Carbamazepine has been used as AEDs since 1965, and is most effective against partial seizures. Two basic mechanisms of action have been proposed: 1) enhancement of sodium channel inactivation by reducing high-frequency repetitive firing of action potentials, 2) and action on synaptic transmission. The aim of this study was to provide a review of(More)
PURPOSES To determine (1)H-MRSI metabolites changes in interictal and postictal phases of patients suffering from mesial temporal lobe epilepsy with hippocampal sclerosis and lateralization of seizure foci. MATERIALS AND METHODS MR spectroscopic imaging was performed in 5 adult patients with refractory temporal lobe epilepsy interictally and immediately(More)
BACKGROUND The challenge of antiepileptic drugs (AEDs) management is to attain the best compromise between the desire to maximize seizure control and the need to keep side-effects within tolerable limits for the individual patient. To reduce devastation in Iranian epileptic patients, the aim of this study was to explore the overall outcome following AEDs(More)
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