Jafar Jafari

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Pain is a ubiquitous yet highly variable experience. The psychophysiological and genetic factors responsible for this variability remain unresolved. We hypothesised the existence of distinct human pain clusters (PCs) composed of distinct psychophysiological and genetic profiles coupled with differences in the perception and the brain processing of pain. We(More)
Swallowing induces an inhibitory wave that is followed by a contractile wave along the esophageal body. Deglutitive inhibition in the skeletal muscle of the esophagus is controlled in the brain stem whilst in the smooth muscle, an intrinsic peripheral control mechanism is critical. The latency between swallow and contractions is determined by the pattern of(More)
This study builds a linear expenditure model for demand analysis of domestic US tourism. The model starts with the assumption of consumer utility maximization under budget constraints and uses five commodity groups: transportation, lodging, food service, entertainment/ recreation, and other goods and services. The findings suggest that among the(More)
High-resolution esophageal manometry (HRM) is a recent development used in the evaluation of esophageal function. Our aim was to assess the inter-observer agreement for diagnosis of esophageal motility disorders using this technology. Practitioners registered on the HRM Working Group website were invited to review and classify (i) 147 individual water(More)
We present a case of a patient with sarcoidosis and who subsequently developed dysphagia for solids, and some difficulty in swallowing liquids. High-resolution manometry of the oesophagus showed absent peristalsis in the oesophageal body and incomplete relaxation of the lower oesophageal sphincter. The diagnosis of sarcoidosis with oesophageal involvement(More)
BACKGROUND & AIMS Management of patients with dysphagia, regurgitation, and related symptoms after antireflux surgery is challenging. This prospective, case-control study tested the hypothesis that compared with standard high-resolution manometry (HRM) with single water swallows (SWS), adding multiple water swallows (MWS) and a solid test meal increases(More)
BACKGROUND Normal values of the esophageal motor function parameters for high-resolution manometry (HRM-EPT) adopted by the Chicago classification were established using the proprietary system of Given Imaging. It is conceivable that normal values of a system do not apply to data from others. Most studies using HRM were based on supine swallows, whereas(More)
OBJECTIVE Gastro-oesophageal reflux is considered to be an important contributing factor in chronic unexplained cough. It remains unclear why some reflux episodes in the same patient causes cough while others do not. To understand more about the mechanism by which reflux induces cough, we aimed to identify factors which are important in triggering cough. (More)
This article analyses the nature and consequences of paradigms in tourism studies. It is somewhat unconventional in that its co-authors have not sought to produce a synthesised finished product. Rather they have rendered their different perspectives visible through the structuring of the article as a trialogue. It commences with Tribe’s thesis that tourism(More)
John Tribe University of Surrey, UK John Tribe is Professor of Tourism at the University of Surrey (Guildford GU2 7XH, United Kingdom. Email <j.tribe@surrey.ac.uk>). He has authored books on philosophy, strategy, economics, education, research and environmental management and his research concentrates on epistemology, education, and sustainability. He is(More)