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DNA nanostructures have been attractive due to their structural properties resulting in many important breakthroughs especially in controlled assemblies and many biological applications. Here, we report a unique energy storage device which is a supercapacitor that uses nanostructured DNA hydrogel (Dgel) as a template and layer-by-layer (LBL)-deposited… (More)
A DNA hydrogel is reported as a delivery vehicle for gold nanorods and doxorubicin. The two photothermal and chemo cancer agents were co-loaded using electrostatic and DNA binding interactions, respectively. Light-triggered and highly synergistic combination cancer therapy was demonstrated in cellular and animal models.
A series of quantum dot (QD) ligands are reported that can make strong polyelectrolyte QD surfaces with sulfonates or quaternary ammoniums, which can endow QDs with excellent colloidal stability independent of the pH and ionic strength, minimal hydrodynamic size, and can be exploited to achieve stable and flexible bioconjugations and layer-by-layer assembly.
The effect of the trehalose incorporation on the nanomechanical properties of dipalmitoylphosphatidylcholine vesicles was studied using atomic force microscope (AFM) on mica surface. The vesicles were prepared only with the variation in the trehalose concentration and adsorbed on the mica surface. After the morphology of the adsorbed vesicles was… (More)
Structural analysis of branched DNA molecules (BDM) is important as model systems for DNA junctions and also as building units for DNA assembly. Although there have been efforts to study the structures of BDM, label-free solution structures have not been well determined yet. Here, we used a combination of synchrotron-based experimental tools and… (More)