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Distinct role of spleen tyrosine kinase in the early phosphorylation of inhibitor of kappaB alpha via activation of the phosphoinositide-3-kinase and Akt pathways.
- Y. Lee, B. Chain, Jae Youl Cho
- Chemistry, Medicine
- The international journal of biochemistry & cell…
- 1 April 2009
Nuclear factor (NF)-kappaB activation is a critical step in the triggering of inflammatory responses by macrophages. Although numerous investigations have been reported, the precise regulatory… Expand
Complete mitochondrial genome of a large-footed bat, Myotis macrodactylus (Vespertilionidae)
Abstract The complete mitochondrial genome was sequenced and characterized newly from a large-footed bat, Myotis macrodactylus (Vespertilionidae). The total length of the M. macrodactylus genome is… Expand
Src-mediated regulation of inflammatory responses by actin polymerization.
- Joo Young Kim, Y. Lee, +6 authors Jae Youl Cho
- Biology, Medicine
- Biochemical pharmacology
- 1 February 2010
Although the role of the actin cytoskeleton has become increasingly elucidated, the role of actin polymerization in inflammatory processes remains poorly understood. Here, we examine the role of the… Expand
In vivo and in vitro anti-inflammatory activities of Persicaria chinensis methanolic extract targeting Src/Syk/NF-κB.
- M. Hossen, Kwang-Soo Baek, +8 authors Jae Youl Cho
- Biology, Medicine
- Journal of ethnopharmacology
- 15 January 2015
ETHNOPHARMACOLOGIC RELEVANCE Persicaria chinensis L. (Polygonaceae) [also synonym as Polygonum chimnense L.] has been used as Chinese traditional medicine to treat ulcer, eczema, stomach ache, and… Expand
Inhibition of 2,4-dinitrofluorobenzene-induced atopic dermatitis by topical application of the butanol extract of Cordyceps bassiana in NC/Nga mice.
ETHNOPHARMACOLOGICAL SIGNIFICANCE The Cordyceps species are insect-borne mushrooms that have been ethnopharmacologically used for skin diseases such as eczema and dermatitis. AIM OF THE STUDY In… Expand
Effects of dialkoxylphenyl compounds with oxime group on macrophage function and the proliferation of lymphocytes
- E. Yoo, E. Yoo, +6 authors Jae Youl Cho
- Medicine, Chemistry
- The Journal of pharmacy and pharmacology
- 1 April 2004
Dialkoxyphenyl compounds have been reported to possess anti‐inflammatory activity through inhibition of phosphodieseterase (PDE) type IV. In this study, a series of derivatives of dialkoxyphenyl… Expand
Mitogen activated protein kinases are prime signalling enzymes in nitric oxide production induced by soluble β-glucan from Sparassis crispa
- Song Yi Lee, Y. Lee, +7 authors Jae Youl Cho
- Biology, Medicine
- Archives of pharmacal research
- 30 November 2010
Sparassis crispa (SC) is an edible mushroom that harbours β-glucans reported to possess immunostimulatory and anticancer properties. The role of SC in regulating the functional activation of… Expand
In vitro and in vivo anti-inflammatory activity of Phyllanthus acidus methanolic extract.
ETHNOPHARMACOLOGICAL RELEVANCE Phyllanthus acidus (L.) Skeels (Phyllanthaceae) has traditionally been used to treat gastric trouble, rheumatism, bronchitis, asthma, respiratory disorders, and… Expand
AP-1 pathway-targeted inhibition of inflammatory responses in LPS-treated macrophages and EtOH/HCl-treated stomach by Archidendron clypearia methanol extract.
ETHNOPHARMACOLOGICAL RELEVANCE Archidendron clypearia Jack. (Fabaceae) is a representative ethnomedicinal herbal plant prescribed for various inflammatory diseases such as pharyngolaryngitis and… Expand
Intraspecific comparison of complete mitogenome sequences from two Asian raccoon dogs (Canidae: Nyctereutes procyonoides)
Abstract We determined the complete mitochondrial genome (GenBank accession number: KF709435) of the Korean raccoon dog Nyctereutes procyonoides koreensis and compared it with a previously published… Expand