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- Publications
- Influence
Acidic pH shock induces the expressions of a wide range of stress-response genes
- Y. Kim, M. H. Moon, Jae Yang Song, C. P. Smith, S. Hong, Y. Chang
- Biology, Medicine
- BMC Genomics
- 16 December 2008
BackgroundEnvironmental signals usually enhance secondary metabolite production in Streptomycetes by initiating complex signal transduction system. It is known that different sigma factors respond to… Expand
Diagnosis of HNF-1α mutations on a PNA zip-code microarray by single base extension
- Jae Yang Song, H. Park, Sung-ouk Jung, Jaechan Park
- Biology, Medicine
- Nucleic acids research
- 1 February 2005
In the present study, we exploited the superior features of peptide nucleic acids (PNAs) to develop an efficient PNA zip-code microarray for the detection of hepatocyte nuclear factor-1α (HNF-1α)… Expand
Fluorescence-based assay formats and signal amplification strategies for DNA microarray analysis
- H. Park, Jae Yang Song, K. H. Park, Min Hwan Kim
- Computer Science
- 1 February 2006
TLDR
pH shock induces overexpression of regulatory and biosynthetic genes for actinorhodin productionin Streptomyces coelicolor A3(2)
- Y. Kim, Jae Yang Song, M. H. Moon, C. P. Smith, S. Hong, Y. Chang
- Biology, Medicine
- Applied Microbiology and Biotechnology
- 4 July 2007
Actinorhodin production is markedly enhanced when an acidic pH shock is applied to a surface-grown culture of Streptomyces coelicolor A3(2). For an in-depth study of this phenomenon, transcriptional… Expand
Identification and characterization of a novel β-galactosidase from Victivallis vadensis ATCC BAA-548, an anaerobic fecal bacterium
- U. Temuujin, Won-Jae Chi, Jae-sun Park, Yong-Keun Chang, Jae Yang Song, S. Hong
- Biology, Medicine
- Journal of Microbiology
- 30 December 2012
Victivallis vadensis ATCC BAA-548 is a Gram-negative, anaerobic bacterium that was isolated from a human fecal sample. From the genomic sequence of V. vadensis, one gene was found to encode agarase;… Expand
Enhancement of geldanamycin production by pH shock in batch culture of Streptomyces hygroscopicus subsp. duamyceticus.
- Jae Yang Song, Y. Kim, Y. Hong, Y. Chang
- Chemistry, Medicine
- Journal of microbiology and biotechnology
- 1 May 2008
Various sequences of pH change were applied in a batch bioreactor to investigate pH shock effects on geldanamycin production by Streptomyces hygroscopicus subsp. duamyceticus JCM4427. In the control… Expand
Effects of pH shock on the secretion system in Streptomyces coelicolor A3(2).
- Y. Kim, Jae Yang Song, S. Hong, C. P. Smith, Y. Chang
- Biology, Medicine
- Journal of microbiology and biotechnology
- 1 April 2008
Effects of pH shock on the secretion system of S. coelicolor A3(2) have been investigated at a transcriptional level by using DNA microarrays. Actinorhodin secretion was observed to be highly… Expand
Gene-expression analysis of acidic pH shock effects on two-component systems in Streptomyces coelicolor
- Y. Kim, An Na Moon, Jae Yang Song, E. Kim, C. Kim, Y. Chang
- Biology
- 5 November 2009
In this study, transcriptional analyses by using reverse transcription-polymerase chain reaction (RT-PCR), DNA chip, and quantitative real time-PCR were performed to investigate effects of acidic pH… Expand
Heterologous expression of a putative K+/H+ antiporter of S. coelicolor A3(2) enhances K+, acidic-pH shock tolerances, and geldanamycin secretion.
- Jae Yang Song, Young Bin Seo, S. Hong, Y. Chang
- Biology, Medicine
- Journal of microbiology and biotechnology
- 1 February 2013
Heterologous expression of a putative K+/H+ antiporter of Streptomyces coelicolor A3(2) (designated as sha4) in E. coli and Streptomyces hygroscopicus JCM4427 showed enhanced tolerance to K+ stress,… Expand