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Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

• Qing Lan, Chao A. Hsiung, +128 authors Nathaniel Rothman
• Nature Genetics
• 2012

To identify common genetic variants that contribute to lung cancer susceptibility, we conducted a multistage genome-wide association study of lung cancer in Asian women who never smoked. We scanned… (More)

The 5p15.33 Locus Is Associated with Risk of Lung Adenocarcinoma in Never-Smoking Females in Asia

• C. Hsiung, Qing Lan, +77 authors Dongxin Lin
• PLoS genetics
• 2010

Genome-wide association studies of lung cancer reported in populations of European background have identified three regions on chromosomes 5p15.33, 6p21.33, and 15q25 that have achieved genome-wide… (More)

Association study of TP53 polymorphisms with lung cancer in a Korean population

• Hae-Yun Jung, Young Mi Whang, +7 authors Yeul Hong Kim
• Journal of Human Genetics
• 2008

AbstractThe tumor suppressor gene, TP53, is located on chromosome 17p13.1 and is critical for DNA repair, cell-cycle control, and apoptosis. TP53 also plays a crucial function in the tumorigenesis of… (More)

Can serum be used for analyzing the EGFR mutation status in patients with advanced non-small cell lung cancer?

• Seung Tae Kim, Hae-Yun Jung, +7 authors Yeul Hong Kim
• American journal of clinical oncology
• 2013

BACKGROUND Epidermal growth factor receptor (EGFR) mutations as prognostic or predictive marker in patients with non-small cell lung cancer (NSCLC) have been used widely. However, it may be difficult… (More)

Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia.

• Mitchell J. Machiela, C. Hsiung, +129 authors Qing Lan
• International journal of cancer
• 2015

Recent evidence from several relatively small nested case-control studies in prospective cohorts shows an association between longer telomere length measured phenotypically in peripheral white blood… (More)

Can mutations of EGFR and KRAS in serum be predictive and prognostic markers in patients with advanced non-small cell lung cancer (NSCLC)?

• Seung Tae Kim, Jae Sook Sung, Uk Jo, Kyong Hwa Park, Sang Shin, Yeul Hong Kim
• Medical oncology
• 2013

The status of epidermal growth factor receptor (EGFR) and Kirsten ras (KRAS) mutations has been used widely in management of patients with non-small cell lung cancer (NSCLC). However, it may be… (More)

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.

• Joshua N. Sampson, William A. Wheeler, +405 authors Nilanjan Chatterjee
• Journal of the National Cancer Institute
• 2015

BACKGROUND Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the… (More)

Single nucleotide polymorphisms of IGFBP-3 gene and lung cancer risk in a Korean population.

• Sle Gi Lo Han, Kyong Hwa Park, +9 authors Yeul Hong Kim
• Lung cancer
• 2008

Insulin-like growth factor binding protein-3 (IGFBP-3) is a putative tumor suppressor and inhibits the mitogenic and antiapoptotic activity of insulin-like growth factor (IGF) by blocking the binding… (More)

Wnt5a Is Associated with Cigarette Smoke-Related Lung Carcinogenesis via Protein Kinase C

• Young Mi Whang, Ukhyun Jo, +6 authors Yeul Hong Kim
• PloS one
• 2013

Wnt5a is overexpressed during the progression of human non-small cell lung cancer. However, the roles of Wnt5a during smoking-related lung carcinogenesis have not been clearly elucidated. We… (More)

Genomic alterations of chromosome region 11p as predictive marker by array comparative genomic hybridization in lung adenocarcinoma patients.

• Jae Sook Sung, Kyong Hwa Park, Yeul Hong Kim
• Cancer genetics and cytogenetics
• 2010

Array comparative genomic hybridization (aCGH) provides a method to quantitatively measure the changes of DNA copy number with an extremely high resolution and to map them directly onto the complete… (More)

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