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Evaluation of a Standardized Extract from Morus alba against α-Glucosidase Inhibitory Effect and Postprandial Antihyperglycemic in Patients with Impaired Glucose Tolerance: A Randomized Double-Blind…

SEMA showed excellent potential in the present study as a material for improving postprandial hyperglycemia as well as evaluating blood glucose reduction in animals and in patients with impaired glucose tolerance in a randomized double-blind clinical trial.
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Inhibitory Effects of Colocasia esculenta (L.) Schott Constituents on Aldose Reductase

Results suggest that flavonoid derivatives from Colocasia esculenta (L.) Schott represent potential compounds for the prevention and/or treatment of diabetic complications.
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Antiproliferative properties of Saussurea lappa Clarke root extract in SH-SY5Y neuroblastoma cells via intrinsic apoptotic pathway

It is demonstrated that the growth inhibitory and cytotoxic effects of SLRE on SH-SY5Y cells are accomplished through the mitochondria-mediated pathway, and that this natural extract might be useful as an anticancer agent for neuroblastoma treatment.
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Morus alba Accumulates Reactive Oxygen Species to Initiate Apoptosis via FOXO-Caspase 3-Dependent Pathway in Neuroblastoma Cells

It is suggested that MARE produces more cytotoxicity in cancer cells while having a relatively attenuated effect on normal cells, and may be a safer option in cancer therapeutics, and it also shows potential for the patients with symptoms of hyperglycemia and cancer.
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Effect of Sulfonylureas Administered Centrally on the Blood Glucose Level in Immobilization Stress Model

  • N. SharmaY. Sim H. Suh
  • Medicine, Biology
    Korean Journal of Physiology and Pharmacology
  • 30 April 2015
The results suggest that lowering effect of sulfonylureas administered supraspinally against immobilization stress-induced increase of the blood glucose level appears to be primarily mediated via elevation of the plasma insulin level.
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Antinociceptive effect of chrysin in diabetic neuropathy and formalin-induced pain models

The results suggest that chrysin shows an antinociceptive property in formalin-induced pain and diabetic neuropathy models, and spinal opioid receptors and CREB protein appear to mediate chrys in-induced ant inociception in the formalin -induced pain model.
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Enhancement of Short-Term Memory by Methyl-6-(Phenylethynyl)-Pyridine in the BTBR T+tf/J Mouse Model of Autism Spectrum Disorder

The results suggest that the BTBR mouse model may be useful in pharmacological studies investigating drugs that could potentially alleviate cognitive dysfunction in ASD and suggests that the mGluR5 antagonist MPEP has the potential to ameliorate learning and memory dysfunction and impaired motor coordination in BTBR mice.
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Telomere length and telomerase activity are related with immortalization frequency but not with replicative senescence in mammalian embryonic fibroblasts, except human embryonic fibroblasts

Results indicate that telomere length and telomerase activity are related with immortalization frequency but not replicative senescence in mammalian fibroblasts, except human fibro Blasts.
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Modulation of corticosterone and changes of signal molecules in the HPA axis after cold water swimming stress

The results suggest that the upregulation of plasma CORT level induced by CWSS may be modulated by the those signaling molecules altered after stress in the HPA axis.
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Application of in utero electroporation of G-protein coupled receptor (GPCR) genes, for subcellular localization of hardly identifiable GPCR in mouse cerebral cortex.

It is demonstrated that neuronal migration in the cerebral cortex was not affected by the overexpression of LPA1, and the protein expression of L PA1 was mainly located in the ventricular zone and cortical plate within the developing mouse cerebral cortex.
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