α-Synuclein (α-Syn), a major component of Lewy body that is considered as the hallmark of Parkinson's disease (PD), has been implicated in neuroexocytosis. Overexpression of α-Syn decreases the neurotransmitter release. However, the mechanism by which α-Syn buildup inhibits the neurotransmitter release is still unclear. Here, we investigated the effect of… (More)
Song, Jaekyun, "A single molecular study of the regulation of SNARE-mediated membrane fusion" (2014). Graduate Theses and Dissertations. Paper 14022.