Jae Keun Yoo

Learn More
BACKGROUND Changes in microRNA (miRNA) expression patterns have been extensively characterized in several cancers, including human colon cancer. However, how these miRNAs and their putative mRNA targets contribute to the etiology of cancer is poorly understood. In this work, a bioinformatics computational approach with miRNA and mRNA expression data was(More)
Generalized linear models with random effects are often used to explain the serial dependence of longitudinal categorical data. Marginalized random effects models (MREMs) permit likelihood-based estimations of marginal mean parameters and also explain the serial dependence of longitudinal data. In this paper, we extend the MREM to accommodate multivariate(More)
  • 1