Jae Hyun Park

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Human mesenchymal stem cells (hMSCs) have generated a great deal of interest in clinical applications. The reason is that they may have the plasticity needed to differentiate into multiple lineages and the ability to expand ex vivo. For the therapeutic applications of hMSCs to be of practical use, it is crucial to assess the efficacy and safety of hMSCs in(More)
OBJECTIVES The objective of this study is to estimate the economic costs of cancer on society. METHODS We estimated the economic burden of people with cancer in South Korea. To perform the analysis, we reviewed the records of people who were cancer patients and those who were newly diagnosed with cancer. The data was compiled from the National Health(More)
Query term ranking approaches are used to select effective terms from a verbose query by ranking terms. Features used for query term ranking and selection in previous work do not consider grammatical relationships between terms. To address this issue, we use syntactic features extracted from dependency parsing results of verbose queries. We also modify the(More)
Caffeic acid phenethyl ester (CAPE), an the active component of propolis, is known to have anticarcinogenic, antiviral and various biological activities; however, the effect of CAPE on the immunomodulatory activity in vivo remains unknown. We have investigated the effect of CAPE on the immune system in female Balb/c mice. CAPE (0, 5, 10, 20 mg/kg) was given(More)
This article reviews the etiology and treatment of open gingival embrasures or black triangles. An open gingival embrasure or black triangle occurs as a result of a deficiency of papilla beneath the contact point. The treatment of open embrasures may require restorative, orthodontic and periodontal considerations depending on the underlying etiology. The(More)
OBJECTIVE To analyze the effect of low-level laser therapy (LLLT) on perception of pain after separator placement and compare it with perceptions of control and placebo groups using a frequent irradiation protocol. MATERIALS AND METHODS Eighty-eight patients were randomly allocated to a laser group, a light-emitting diode (LED) placebo group, or a control(More)
The embryonic stem cell-like gene expression signature has been shown to be associated with poorly differentiated aggressive human tumors and has attracted great attention as a potential target for future cancer therapies. Here, we investigate the potential of the embryonic stem cell signature as molecular target for the therapy and the strategy to suppress(More)
Using a mouse model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease (PD), this study investigated on the neuroprotective effects of acupuncture by examining whether acupuncture contributed to inhibiting microglial activation and inflammatory events. C57BL/6 mice were treated with MPTP (30 mg/kg, i.p.) for 5 consecutive(More)
IMPORTANCE Cerebrovascular disease (CVD) and Alzheimer disease are significant causes of cognitive impairment in the elderly. However, few studies have evaluated the relationship between CVD and β-amyloid burden in living humans or their synergistic effects on cognition. Thus, there is a need for better understanding of mild cognitive impairment (MCI)(More)