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Studies with the Human Cohesin Establishment Factor, ChlR1
Findings are consistent with a role of hChlR1 in the establishment of sister chromatid cohesion and suggest that its action may contribute to lagging strand processing events important in cohesion.
Silicon mitigates heavy metal stress by regulating P-type heavy metal ATPases, Oryza sativa low silicon genes, and endogenous phytohormones
The present study supports the active role of Si in the regulation of stresses from heavy metal exposure through changes in root morphology and shows a significant up-regulation of mRNA expression with Si treatment in rice plants.
NEONATAL EXPOSURE TO DI(N-BUTYL) PHTHALATE (DBP) ALTERS MALE REPRODUCTIVE-TRACT DEVELOPMENT
- Hyung Sik Kim, Tae Sung Kim, S. Han
- Biology, MedicineJournal of toxicology and environmental health…
- 1 December 2004
The data suggest that DBP is likely to exert its antiandrogenic actions through disruption of AR or ERβ expression during the early neonatal stage, and that neonatal exposure to DBP produces permanent changes in the endocrine system and leads to abnormal male reproductive-tract development until puberty.
Structural polymorphism of Methanothermobacter thermautotrophicus MCM.
Evaluation of the 20-day pubertal female assay in Sprague-Dawley rats treated with DES, tamoxifen, testosterone, and flutamide.
- Hyung Sik Kim, Jae-Ho Shin, S. Han
- Biology, MedicineToxicological sciences : an official journal of…
- 1 May 2002
The data demonstrate that the rodent pubertal female assay is useful for identifying potential EDs having not only estrogenic/antiestrogenic but also androgenic/antiandrogenic activities, however, further validation study is necessary to identify chemicals that operate through other action mechanisms, including steroid biosynthesis inhibitors and thyroid inhibitors.
A biochemically active MCM-like helicase in Bacillus cereus
It is shown that BcMCM displays 3′→5′ helicase and ssDNA-stimulated ATPase activity, properties that arise from its conserved AAA domain, and proposed that the divergent amino-terminus of Bc MCM is a paralog of the corresponding region of MCM-helicases.
Benzaldehyde as an insecticidal, antimicrobial, and antioxidant compound produced by Photorhabdus temperata M1021
The results suggest that benzaldehyde could be applicable for developing novel insecticide for agriculture use and has great antioxidant activity and maximum antioxidant activity was 52.9% at 8 mM benzaldehyde as compare to control.
Assessing estrogenic activity of pyrethroid insecticides using in vitro combination assays.
- In Y Kim, Jae-Ho Shin, S. Han
- Biology, MedicineThe Journal of reproduction and development
- 1 April 2004
Certain pyrethroid insecticides may be considered to be estrogen-like chemicals that act through pathways other than direct ER binding, and may function as endocrine modulators in both wildlife and humans.
Biochemical Characterization of the Methanothermobacter thermautotrophicus Minichromosome Maintenance (MCM) Helicase N-terminal Domains*
- R. Kasiviswanathan, Jae-Ho Shin, E. Melamud, Z. Kelman
- BiologyJournal of Biological Chemistry
- 2 July 2004
Using biochemical and biophysical analyses it is shown that domain C of the N-terminal portion of the Methanothermobacter thermautotrophicus minichromosome maintenance helicase is required for protein multimerization and that domain B is the main contact region with single-stranded DNA.
Full-Genome Sequence Analysis of a Variant Strain of Porcine Epidemic Diarrhea Virus in South Korea
- Sunhee Lee, Gun-seok Park, Jae-Ho Shin, Changhee Lee
- Biology, EngineeringGenome Announcements
- 20 November 2014
The complete genome of the KOR/KNU-1406/2014 strain was sequenced and analyzed to investigate the U.S. variant strain OH851 circulating in South Korea.