Jacqueline Reihman

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We examined the relationship between prenatal (cord blood) polychlorinated biphenyls (PCBs) and Neonatal Behavioral Assessment Scale (NBAS) performance in babies born to women who consumed contaminated Lake Ontario fish. Cord blood PCBs, DDE, HCB, Mirex, lead, and hair mercury levels were determined for 152 women who reported never consuming Lake Ontario(More)
A sample of infants was examined at conceptual age 67 weeks (6-month testing, N=230), and again at conceptual age 92 weeks (12-month testing, N=216) using the Fagan Test of Infant Intelligence (FTII). Analysis of the results revealed a dose-dependent relationship between total umbilical cord-blood PCB levels and poorer FTII performance at both ages. A(More)
A number of epidemiological studies have shown predictive relationships between prenatal exposure to polychlorinated biphenyls (PCBs) and subtle deficits in cognitive development in infancy through the preschool years [Child Dev. 56 (1985) 853; J. Pediatr. 116 (1990) 38; J. Pediatr. 134 (1999) 33; Toxicol. Lett. 102-103 (1998) 423; Neurotox. 21 (6) (2000)(More)
The present study reports the association between prenatal exposure to polychlorinated biphenyls (PCBs), the corpus callosum, and response inhibition in children who are 4.5 years old. Children (n = 189) enrolled in the Oswego study were tested using a continuous performance test. We measured (square millimeters) the splenium of the corpus callosum, a(More)
BACKGROUND Animal studies have shown that exposure to common, low-level environmental contaminants [e.g., polychlorinated biphenyls (PCBs), lead] causes excessive and inappropriate responding on intermittent reinforcement schedules. The Differential Reinforcement of Low Rates task (DRL) has been shown to be especially sensitive to low-level PCB exposure in(More)
We previously reported a relationship between prenatal PCB exposure and impulsive (excessive) responding on a continuous performance task in children at 4 1/2 years of age [P.W. Stewart, S. Fitzgerald, J. Reihman, B. Gump, E. Lonky, T. Darvill, J. Pagano, P. Hauser, Prenatal PCB exposure, the corpus callosum, and response inhibition, Environmental Health(More)
BACKGROUND Several epidemiologic studies have demonstrated relationships between prenatal exposure to polychlorinated biphenyls (PCBs) and modest cognitive impairments in infancy and early childhood. However, few studies have followed cohorts of exposed children long enough to examine the possible impact of prenatal PCB exposure on psychometric intelligence(More)
This study investigated the effects of consumption of Great Lakes fish on progressive ratio performance, and on the pattern and concentrations of brain polychlorinated biphenyls (PCBs), dichlorodiphenyldichloroethene (DDE), and mirex in the rat. Adult, male Sprague-Dawley rats were fed a 30% diet of either Lake Ontario salmon (LAKE), Pacific Ocean salmon,(More)
The current study was designed to assess the pattern and concentration of prenatal PCB exposure in the newborns of women who consumed Great Lakes fish. We compared the pattern and concentration of umbilical cord blood PCBs of 145 women who reported never having consumed Great Lakes fish to 134 women who reported consuming at least 40 PCB-equivalent fish lbs(More)
The literature concerning the relationship between polychlorinated biphenyl (PCB) exposure and Intelligence (IQ) is not entirely consistent. Two studies showed inverse associations between PCBs and IQ in cohorts of children whose mothers consumed Great Lakes fish contaminated with PCBs and other organochlorines (Jacobson & Jacobson 1996; Stewart et al.(More)