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  • J. P. Bastard, Claude Jardel, +5 authors Bernard Hainque
  • Medicine
  • The Journal of clinical endocrinology and…
  • 2000 (First Publication: 1 September 2000)
  • The aim of this study was to investigate the potential role of adipose cytokines in the obesity-associated insulin resistance. To that end, we compared: 1) serum concentrations of interleukin 6Continue Reading
  • Jean-Philippe Bastard, Mustapha Maachi, +6 authors Bernard Hainque
  • Medicine
  • The Journal of clinical endocrinology and…
  • 2002 (First Publication: 1 May 2002)
  • Obesity and type 2 diabetes are associated with insulin resistance, the mechanisms of which remain poorly understood. A significant correlation between circulating IL-6 level and insulin sensitivityContinue Reading
  • Claire Lagathu, J. -P. Bastard, Martine Auclair, Mustapha Maachi, Jacqueline Capeau, Martine Caron
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 2003 (First Publication: 1 November 2003)
  • IL-6 has emerged as an important cytokine upregulated in states of insulin resistance such as type 2 diabetes. We evaluated the chronic effect of IL-6 on insulin signaling in 3T3-F442A and 3T3-L1Continue Reading