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Thalamic neurodegeneration in multiple sclerosis
- A. Cifelli, M. Arridge, P. Jezzard, M. Esiri, Jacqueline A Palace, P. Matthews
- Annals of neurology
- 1 November 2002
Multiple sclerosis is still regarded primarily as a disease of the white matter. However, recent evidence suggests that there may be significant involvement of gray matter. Here, we have used… Expand
MRI characteristics of neuromyelitis optica spectrum disorder
Since its initial reports in the 19th century, neuromyelitis optica (NMO) had been thought to involve only the optic nerves and spinal cord. However, the discovery of highly specific anti–aquaporin-4… Expand
Myelin-oligodendrocyte glycoprotein antibodies in adults with a neuromyelitis optica phenotype
Objectives: To report an association of myelin-oligodendrocyte glycoprotein (MOG) antibodies with aquaporin-4 (AQP4) antibody–seronegative neuromyelitis optica (NMO) and neuromyelitis optica spectrum… Expand
Neuromyelitis optica spectrum disorders with aquaporin-4 and myelin-oligodendrocyte glycoprotein antibodies: a comparative study.
IMPORTANCE Most patients with neuromyelitis optica (NMO) and many with NMO spectrum disorder have autoantibodies against aquaporin-4 (AQP4-Abs), but recently, myelin-oligodendrocyte glycoprotein… Expand
Aquaporin-4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitis.
BACKGROUND There is increasing recognition of antibody-mediated immunotherapy-responsive neurologic diseases and a need for appropriate immunoassays. OBJECTIVES To develop a clinically applicable… Expand
MRI CRITERIA FOR THE DIAGNOSIS OF MULTIPLE SCLEROSIS: MAGNIMS CONSENSUS GUIDELINES
Summary In patients presenting with a clinically isolated syndrome (CIS), magnetic resonance imaging (MRI) can support and substitute clinical information for multiple sclerosis (MS) diagnosis… Expand
International consensus guidance for management of myasthenia gravis
Objective: To develop formal consensus-based guidance for the management of myasthenia gravis (MG). Methods: In October 2013, the Myasthenia Gravis Foundation of America appointed a Task Force to… Expand
Congenital myasthenic syndromes due to mutations in ALG2 and ALG14
- J. Cossins, K. Belaya, +16 authors D. Beeson
- Biology, Medicine
- Brain : a journal of neurology
- 11 February 2013
Congenital myasthenic syndromes are a heterogeneous group of inherited disorders that arise from impaired signal transmission at the neuromuscular synapse. They are characterized by fatigable muscle… Expand
Interferon Beta treatment in neuromyelitis optica: increase in relapses and aquaporin 4 antibody titers.
OBJECTIVE To describe a patient with neuromyelitis optica (NMO) whose aquaporin 4 (AQP4) antibody levels increased following treatment with interferon beta. DESIGN Prospective clinical and… Expand
Guidelines on use of anti‐IFN‐β antibody measurements in multiple sclerosis: report of an EFNS Task Force on IFN‐β antibodies in multiple sclerosis
- P. S. Sørensen, F. Deisenhammer, +6 authors C. Ross
- European journal of neurology
- 1 November 2005
Therapy‐induced binding and neutralizing antibodies is a major problem in interferon (IFN)‐β treatment of multiple sclerosis. The objective of this study was to provide guidelines outlining the… Expand