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Safety, pharmacokinetics, and pharmacodynamics of TV-1380, a novel mutated butyrylcholinesterase treatment for cocaine addiction, after single and multiple intramuscular injections in healthy subjects
- O. Cohen-Barak, Jacqueline A L Wildeman, +8 authors O. Spiegelstein
- Journal of clinical pharmacology
- 12 January 2015
Human plasma butyrylcholinesterase (BChE) contributes to cocaine metabolism and has been considered for use in treating cocaine addiction and cocaine overdose. TV‐1380 is a recombinant protein… Expand
Long-chain polyunsaturated fatty acids have a positive effect on the quality of general movements of healthy term infants.
- H. Bouwstra, D. Dijck-Brouwer, +5 authors M. Hadders-Algra
- The American journal of clinical nutrition
- 1 August 2003
BACKGROUND Whether long-chain polyunsaturated fatty acids (LCPs) play a role in the development of the young nervous system in term infants is debated. OBJECTIVE We investigated whether… Expand