Learn More
Behaviors, from simple to most complex, require a two-way interaction with the environment and the contribution of different brain areas depending on the orchestrated activation of neuronal assemblies. In this work we present a new hybrid neuro-robotic architecture based on a neural controller bi-directionally connected to a virtual robot implementing a(More)
Brain functions are strictly dependent on neural connections formed during development and modified during life. The cellular and molecular mechanisms underlying synaptogenesis and plastic changes involved in learning and memory have been analyzed in detail in simple animals such as invertebrates and in circuits of mammalian brains mainly by intracellular(More)
Brain-machine interfaces (BMI) were born to control "actions from thoughts" in order to recover motor capability of patients with impaired functional connectivity between the central and peripheral nervous system. The final goal of our studies is the development of a new proof-of-concept BMI-a neuromorphic chip for brain repair-to reproduce the functional(More)
Behaviors, from simple to most complex, require a two-way interaction with the environment and the contribution of different brain areas depending on the orchestrated activation of neuronal assemblies. Understanding how information is coded and how synaptic mechanisms are implemented in physiological as well as pathological networks is one of the major(More)
Information coding in the Central Nervous System (CNS) remains unexplored. There is mounting evidence that, even at a very low level, the representation of a given stimulus might be dependent on context and history. If this is actually the case, bi-directional interactions between the brain (or if need be a reduced model of it) and sensory-motor system can(More)
In this study, an in vitro cortical culture was stimulated according to the activity exhibited by its in silico counterpart. We connected the latter, an artificial spiking neural network (SNN), to the former, a biological network (BNN), via an open-loop (i.e. unidirectional) configuration, with the ultimate goal of establishing a closed-loop bidirectional(More)
In this study we investigated the relationship between stimulus regularity and observed responses in a biological neural network of dissociated cortical rat neurons plated over Micro-Electrode Arrays (MEAs). In particular, the intervals between identical stimuli in our experiments followed a 1/f(β) distribution, and regularity increased with the value of β(More)
  • 1