Jacob T Painter

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STUDY OBJECTIVE The combination of vancomycin and piperacillin-tazobactam has been associated with an increased risk of acute kidney injury (AKI) in non-critically ill patient populations, but it is still unknown if this association exists in critically ill patients. The objective of this study was to compare the incidence of AKI development during therapy(More)
Chronic opioid therapy in the treatment of chronic nonmalignant pain has increased drastically over the past decade. This is a worrisome trend in general, but specifically, given pathophysiologic characteristics seen in fibromyalgia (FM) syndrome patients, the use of this class of medication deserves special scrutiny. We first describe the current(More)
PURPOSE The current epidemic of prescription opioid abuse and misuse in the United States is discussed, with an emphasis on the pharmacist's role in ensuring safe and effective opioid use. SUMMARY U.S. sales of prescription opioids increased fourfold from 1999 to 2010, with an alarming rise in deaths and emergency department visits associated with the use(More)
BACKGROUND Opioid use for the treatment of chronic nonmalignant pain has increased drastically over the past decade. Although no evidence of efficacy exists supporting the treatment of fibromyalgia (FM) with chronic opioid therapy, a large number of patients are receiving this therapy. Geographic variation in the use of opioids has been demonstrated in the(More)
OBJECTIVE To examine the cost-effectiveness of the HIV Translating Initiatives for Depression Into Effective Solutions (HITIDES) intervention. DESIGN Randomized controlled effectiveness and implementation trial comparing depression collaborative care with enhanced usual care. SETTING Three Veterans Health Administration HIV clinics in the Southern(More)
We examined the effect of ethanol on a complex decision process in honeybees. In many contexts (e.g., flower patches containing both blue and white flowers), honeybees have been shown to make decisions concerning which flowers to visit based on the reward's caloric value offered by competing flower types. However, under some contexts (e.g., flower patches(More)
OBJECTIVES To compare the predictive validity of the 2003 Beers, 2012 American Geriatrics Society (AGS) Beers, and Screening Tool of Older Persons' potentially inappropriate Prescriptions (STOPP) criteria. DESIGN Retrospective cohort. SETTING Managed care administrative claims data from 2006 to 2009. PARTICIPANTS Commercially insured persons aged 65(More)
Background: Clostridium difficile infection (CDI) is a growing clinical and economic burden throughout the world. Pharmacists often are members of the primary care team in the intensive care unit (ICU) setting; however, the impact of pharmacists educating other health care providers on appropriateness of CDI treatment has not been previously examined.(More)
BACKGROUND AND OBJECTIVES Cervical cancer, when detected early by methods like the Pap test, is usually curable. Unfortunately, Pap smear screening is not universal, and mortality from cervical cancer still occurs. The objective of this study was to identify the extent to which female patients were not receiving annual Pap tests in nine family physicians'(More)