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This paper addresses the problem of identification of hybrid dynami-cal systems, by focusing the attention on hinging hyperplanes (HHARX) and Wiener piecewise affine (W-PWARX) autoregressive exogenous models. In particular, we provide algorithms based on mixed-integer linear or quadratic programming which are guaranteed to converge to a global optimum. For(More)
Detecting and isolating multiple faults is a computationally expensive task. It typically consists of computing a set of tests and then computing the diagnoses based on the test results. This paper describes FlexDx, a reconfigurable diagnosis framework which reduces the computational burden while retaining the isolation performance by only running a subset(More)
Type 2 diabetes is characterized by insulin resistance of target organs, which is due to impaired insulin signal transduction. The skeleton of signaling mediators that provide for normal insulin action has been established. However, the detailed kinetics, and their mechanistic generation, remain incompletely understood. We measured time-courses in primary(More)
— Despite the enormous complexity of the human mind, fMRI techniques are able to partially observe the state of a brain in action. In this paper we describe an experimental setup for real-time fMRI in a bio-feedback loop. One of the main challenges in the project is to reach a detection speed, accuracy and spatial resolution necessary to attain sufficient(More)