Preventive effect of diethyldithiocarbamate on experimental diabetes produced by dithisone and 8-oxychinoline.
Diethyldithiocarbamate sodium (DDC)--a compound forming complexes with metal ions-did not change the structure of endocrine pancreas and did not affect the glycemia after the repeated administration… Expand
Studies on diabetes mellitus after ventromedial hypothalamic lesions in adult and aged rats.
The signs of obesity and diabetes in 49 adult and 56 aged female Wistar rats were studied following complete and histologically confirms bilateral lesions of ventromedial hypothalamic nuclei.… Expand
Dithisone diabetes in rabbits and its prevention by sulfhydryl and imidazole containing compounds.
Diabetogenic action of dithisone was investigated in a total of 368 adult rabbits and 53 young animals between 10 h and 31 days of age. The diabetes was found in 95% of animals injected with… Expand
Primary insulin insufficiency after blocking of zinc in pancreatic beta-cells.
Diabetogenic effects of various analogues of 8-aminoquinoline were studied. Out of 10 compounds investigated only three showed diabetogenic properties: 8-(p-tolylsulfonylamino)-quinoline,… Expand