Jaclyn A. Quirt

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The receptor, c-Kit, and its ligand, stem cell factor (SCF), are critical for hematopoietic stem cell differentiation and have been implicated in the development, function, and survival of rodent islets. Previously, we reported that exogenous SCF treatments of cultured human fetal (14-16 wk fetal age) islet-epithelial clusters enhanced islet cell(More)
Li J, Quirt J, Do HQ, Lyte K, Fellows F, Goodyer CG, Wang R. Expression of c-Kit receptor tyrosine kinase and effect on -cell development in the human fetal pancreas. Am J Physiol Endocrinol Metab 293: E475–E483, 2007. First published May 22, 2007; doi:10.1152/ajpendo.00172.2007.—The receptor, c-Kit, and its ligand, stem cell factor (SCF), are critical for(More)
Melioidosis is an infection endemic to Southeast Asia and Northern Australia, and is associated with significant morbidity and mortality. The present report describes a case of chronic melioidosis in a returning traveller from the Philippines. Clinical suspicion of this illness is warranted in individuals with a history of travel to endemic regions. Safety(More)
Norovirus infection causes a significant burden of morbidity and (in the developing world) mortality. In immunocompromised hosts, norovirus infection can become chronic, with devastating consequences. Unfortunately, therapeutic options for chronic disease are unproven, and treatment is largely supportive. We report a case of norovirus infection causing(More)
BACKGROUND Many institutions recommend a stepwise approach to intradermal testing for venom allergy. This is costly and uncomfortable for the patient. The rationale for this approach is the risk of potential adverse reactions to testing with the maximal dose alone. OBJECTIVE To evaluate the safety of a single-step approach to venom allergy testing. (More)
We present two cases of food and exercise-induced anaphylaxis (FEIA) in patients with a diagnosis of oral allergy syndrome (OAS) to the implicated foods. Patient A had FEIA attributed to fresh coriander and tomato and Patient B to fresh celery. These food allergens have been implicated in OAS and have structural antigenic similarity to that of birch and/or(More)
PURPOSE The objective of this study was to examine the characteristics of the medical trainee (resident), the supervisor and the project that contribute to successful completion of resident-led research and publication in a peer-reviewed scientific journal. METHODS Qualitative, interview-based study of Internal Medicine trainees and their supervisors. All(More)
© 2016 The Author(s). This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the(More)
© The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the(More)
Background Infliximab and adalimumab are monoclonal antibodies to tumor necrosis factor alpha (TNF-á) used in the treatment of various inflammatory disorders. Infliximab, a chimeric monoclonal antibody, is postulated to be more immunogenic as it is not entirely humanized. Despite reports of adalimumab treatment in patients after an adverse reaction to(More)
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