Jacklyn H Salmon

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PURPOSE To determine the feasibility, safety, and effectiveness of an episcleral or deep scleral lamellar sustained release cyclosporine (CsA) device in a naturally occurring animal model of uveitis. METHODS A two-compartment perfusion chamber was used to assess in vitro human and equine scleral permeability of fluorescein, dexamethasone-fluorescein, or(More)
PURPOSE To determine the effects and posterior distribution of injections made into the anterior suprachoroidal space (SCS). METHODS The anterior SCS of adult porcine and canine ex vivo eyes was cannulated. Latex injections and high frequency ultrasound (50 MHz) was used to image the effect and distension of the SCS. Flow characteristics and percentage(More)
PURPOSE To evaluate the effect of triamcinolone acetonide (TA) administered into the suprachoroidal space (SCS) using a microneedle and compare it with intravitreal (IVT) TA injections in a porcine model of acute posterior segment inflammation. MATERIALS An IVT injection of balanced salt solution (BSS) or lipopolysaccharide (LPS) was followed 24 hours(More)
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