Jack Yu-Hung Lin

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Automatic detection of pulmonary nodules in thoracic computed tomography (CT) scans has been an active area of research for the last two decades. However, there have only been few studies that provide a comparative performance evaluation of different systems on a common database. We have therefore set up the LUNA16 challenge, an objective evaluation(More)
In humans on a normal diet, about 50% of homocysteine is remethylated to methionine with methyltetrahydrofolate as the methyl donor. Hence, folate deficiency may result in inadequate synthesis of the methyl donor, leading to homocysteine accumulation. Moderate homocysteinemia has been associated with atherosclerotic vascular disorders in humans but other(More)
The effect of folate deficiency on homocysteine metabolism was examined in rats given a folate-deficient diet. Total homocysteine was determined in serum stored at -22 degrees C for 3 wk. All animals in the control group had more than 20 ng.ml-1 of serum folate and more than 1000 pg.ml-1 of serum cyanocobalamin throughout the experimental period. In(More)
A French multidrug protocol for stage III ovarian cancer has achieved 77% pathologic complete response, 100% total response, and 81% actuarial 4-year survival. Our analysis indicates that these rates exceed typical with very high statistical significance. Yet neither the drugs, the combined intravenous and intraperitoneal mode of delivery, nor potential(More)
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