Jack F. M. Wetzels

Learn More
BACKGROUND The Modification of Diet in Renal Disease (MDRD) formula is widely used in clinical practice to assess the correct drug dose. This formula is based on serum creatinine levels which might be influenced by chronic diseases itself or the effects of the chronic diseases. We conducted a systematic review to determine the validity of the MDRD formula(More)
The use of estimated glomerular filtration rate (eGFR) in daily clinical practice. eGFR is a key component in drug therapy management (DTM) in patients with renal impairment. eGFR is routinely reported by laboratories whenever a serum creatinine testing is ordered. In this paper, we will discuss how to use eGFR knowing the limitations of serum(More)
BACKGROUND Early detection and appropriate management of chronic kidney disease (CKD) in primary care are essential to reduce morbidity and mortality. AIM To assess the quality of care (QoC) of CKD in primary healthcare in relation to patient and practice characteristics in order to tailor improvement strategies. DESIGN AND SETTING Retrospective study(More)
OBJECTIVE To determine the relationship between renal function and visit-to-visit blood pressure (BP) variability in a cohort of primary care patients. DESIGN Retrospective cohort study from routinely collected healthcare data. SETTING Primary care in Nijmegen, the Netherlands, from 2007 to 2012. PARTICIPANTS 19 175 patients who had a measure of renal(More)
OBJECTIVE To assess the impact on cardiovascular risk factor management in primary care by the introduction of chronic kidney disease epidemiological collaboration (CKD-EPI) for estimated-glomerular filtration rate (eGFR) reporting. DESIGN AND SETTING Cross-sectional study of routine healthcare provision in 47 primary care practices in The Netherlands(More)
  • 1