Jack A. Clark

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Role functioning and its limitations due to one's health is an important aspect of health-related quality of life (HRQoL). The Medical Outcomes Study (MOS) SF-36 includes 2 role functioning scales: role limitations due to physical health problems (RP) or emotional problems (RE). Although they capture important concepts of HRQoL, these 2 scales have some(More)
BACKGROUND Prostate cancer (PC) mortality is much greater for African American than for Caucasian men. To identify patient factors that might account for some of this disparity, men within 6 months of diagnosis were surveyed about health attitudes and behavior. METHODS Using Rapid Identification in the North Carolina Cancer Registry, 207 African American(More)
PURPOSE To assess the feasibility of early discharge to home therapy with standard intravenous antibiotics in 30 patients with fever and neutropenia at low risk by a validated clinical decision rule. PATIENTS AND METHODS Newly admitted outpatients with fever and neutropenia were evaluated for home therapy during 2 days of inpatient observation. To(More)
PURPOSE Understanding the distinctive patterns of treatment-related dysfunction after alternative initial treatments for early prostate cancer (PC) may improve patients' choice of treatment and later help them adjust to its consequences. We characterized the time course of treatment complications while adjusting for potentially confounding pretreatment(More)
Pressure therapy is generally accepted as the best noninvasive means of preventing and controlling hypertrophic scarring after burn injury. Most studies in the past have failed to correlate clinical response with magnitude of the garment-scar interface pressure. This study looked critically at our usual techniques of pressure therapy using pressure(More)
BACKGROUND Our objective was to develop a patient-based measure of the severity of osteoarthritis of the knee, focusing on symptomatology, that may be used in conjunction with measures of health-related quality of life in monitoring the health status of outpatients. METHODS We surveyed a random sample of male outpatients at Boston-area Veterans Affairs(More)
PURPOSE To examine variation in men's long-term regret of treatment decisions, ie, surgical versus chemical castration, for metastatic prostate cancer and its associations with quality of life. METHODS Survey of previously treated patients to assess treatment decisions and quality of life, supplemented with focus groups. Two items addressing whether a(More)
BACKGROUND Patients' perceptions of treatment outcomes are important in the management of early prostate cancer, but few studies have offered reliable and responsive measures to assess the likely side effects of the most common treatments. OBJECTIVE To develop indexes of urinary, bowel, and sexual function, and related distress. RESEARCH DESIGN(More)
PURPOSE To use data from a prospective quality-of-life study to assess differences in disease-specific and general health-related quality-of-life changes after treatment with different external-beam irradiation techniques for prostate cancer. PATIENTS AND METHODS Patients were divided into three groups based on their pretreatment field size and planning(More)
PURPOSE Transurethral resection, chemotherapy and radiation with salvage cystectomy may be used as alternatives to immediate radical cystectomy in the management of invasive bladder cancer. Concern exists about the function of the retained bladder after such therapy. MATERIALS AND METHODS Of 221 patients with clinical T2-4a bladder cancer treated at(More)