JLAA Falcão

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OBJECTIVE To relate psychological profiles, cerebral asymmetry and the hypothalamus-pituitary-adrenal axis (HPA) reactivity to clinical characteristics of common obesity. METHODS Sixty consecutive adult female overweight and obese patients attending the outpatient endocrine department were included in this study. Clinical evaluation specifically selected(More)
Several D-sugars were incubated with L-lysine or with L-arginine for 10 days. The resulting compounds are able to reduce nitrobluetetrazolium (NBT). This is prevented by superoxide dismutase (SOD), indicating that the superoxide radical is generated by the resulting Amadori compounds. The formation of superoxide radical in vivo, as a result of nonenzymatic(More)
Virtual Histology (VH) is a new medical imaging technique that allows the assessment of atherosclerotic plaque composition, a potential useful tool for the evaluation of individuals with coronary disease. Empirical observation has suggested that plaque areas adjacent to dense calcium (DC) are frequently coded as necrotic core (NC) in VH images. The main(More)
In-vivo atherosclerotic plaque composition has been currently assessed by means of techniques based on spectral analysis of backscattered intravascular ultrasonic signals. Conversely, conventional IVUS images are based only on amplitude envelope of ultrasonic signals, discarding some frequency information and, consequently, disabling tissue characterization(More)
OBJECTIVE To characterize serum lipid abnormalities in overweight and obese female patients and to quantify the relative importance of associated factors. METHODS Cross sectional study at the first visit to the out-patient department. 237 consecutive overweight and obese female patients (age 31 +/- 14 y, body mass index (BMI) 34.2 +/- 6.0 kg/m2) were(More)
Sprague-Dawley rats were separated in 4 groups. G1 received streptozotocin (ST). G2 received nicotinamide (NC) followed by ST. G3 was a NC control and G4 was a citrate control. The rats were sacrificed after 28 h and the islets isolated. Histamine and histaminase were determined. In the islets there was an increase in histamine content in G1 and a smaller(More)
Amino sugars such as galactosamine are hepatotoxic. It has been verified that toxic hepatitis induced by galactosamine is similar to that of CCl4 poisoning, and that both were inhibited by O2* scavengers. Fructosamine results from the union of glucose with the epsilon-amine of lysine. A test for fructosamine quantification is based on nitroblue tetrazolium(More)