JLAA Falcão

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Virtual Histology (VH) is a new medical imaging technique that allows the assessment of atherosclerotic plaque composition, a potential useful tool for the evaluation of individuals with coronary disease. Empirical observation has suggested that plaque areas adjacent to dense calcium (DC) are frequently coded as necrotic core (NC) in VH images. The main(More)
Several D-sugars were incubated with L-lysine or with L-arginine for 10 days. The resulting compounds are able to reduce nitrobluetetrazolium (NBT). This is prevented by superoxide dismutase (SOD), indicating that the superoxide radical is generated by the resulting Amadori compounds. The formation of superoxide radical in vivo, as a result of nonenzymatic(More)
In-vivo atherosclerotic plaque composition has been currently assessed by means of techniques based on spectral analysis of backscattered intravascular ultrasonic signals. Conversely, conventional IVUS images are based only on amplitude envelope of ultrasonic signals, discarding some frequency information and, consequently, disabling tissue characterization(More)
Sprague-Dawley rats were separated in 4 groups. G1 received streptozotocin (ST). G2 received nicotinamide (NC) followed by ST. G3 was a NC control and G4 was a citrate control. The rats were sacrificed after 28 h and the islets isolated. Histamine and histaminase were determined. In the islets there was an increase in histamine content in G1 and a smaller(More)
Amino sugars such as galactosamine are hepatotoxic. It has been verified that toxic hepatitis induced by galactosamine is similar to that of CCl4 poisoning, and that both were inhibited by O2* scavengers. Fructosamine results from the union of glucose with the epsilon-amine of lysine. A test for fructosamine quantification is based on nitroblue tetrazolium(More)
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