JL Marenco

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INTRODUCTION Patients with systemic lupus erythematosus (SLE) have increased cardiovascular risk related to lipid changes induced by inflammatory activity, proteinuria and treatments. Our objective was to analyse lipid changes in a cohort of patients with SLE resistant to standard treatments who were treated with rituximab. METHODS The study population(More)
We report the case of a patient with Behçet's disease who presented with deep vein thrombosis and pulmonary embolism. In spite of being treated initially with anticoagulants, corticosteroid and oral cyclophosphamide, the patient presented again with a new pulmonary embolism. This critical situation made us initiate thrombolytic therapy with a urokinase(More)
OBJECTIVE To evaluate the clinical response and safety profile of infliximab in refractory ankylosing spondylitis patients. METHODS Patients with active ankylosing spondylitis, despite methotrexate therapy, were included in an open-label, single-centre study. Patients were given 3-5 mg/kg infliximab infusions at Weeks 0, 2, 6, and q8 etc up to Week 30,(More)
INTRODUCTION AND OBJECTIVE Systemic lupus erythematosus is a syndrome of variable clinical and immunological expression, which may affect any organ. Stroke is an uncommon complication of systemic lupus erythematosus, attributed to many different etiopathogenic mechanisms such as early atherosclerosis, coagulopathy, vasculitis, cardiogenic embolism, etc. Our(More)
Objectives To analyze RA patients treated with biologics in a University Hospital. Proportion of patients treated with different drugs, as first, second or third choice. To know the disease activity before and after biologic therapy. To know side effects and the reasons. We have reviewed all RA patients treated with biologicals from 1998 to January 2010. We(More)