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Adeno-associated virus-mediated delivery of erythropoietin leads to sustained elevation of hematocrit in nonhuman primates
TLDR
The data demonstrate the potential for long-term gene expression in large animals by a single intramuscular injection of a recombinant adeno-associated virus (rAAV) vector. Expand
Profiling of genes which are differentially expressed in mouse liver in response to adenoviral vectors and delivered genes
TLDR
TheIncreased expression of u-PAR1, laminin receptor and BMP-1 confirms the importance of CTGF and TGFβ1 in angiogenesis, and tissue repair, and the immune response induced by infection with a first generation, replication-incompetent adenovirus. Expand