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Identification of a Peptide Toxin from Grammostola spatulata Spider Venom That Blocks Cation-Selective Stretch-Activated Channels
A 35 amino acid peptide toxin of the inhibitor cysteine knot family that blocks cationic stretch-activated ion channels is identified and implicates SACs in volume regulation. Expand
Proinsulin conversion to desalanyl insulin by α2-macroglobin-bound trypsin
HARPEL and Mosesson1 observed that α2-macroglobulin-bound trypsin hydrolysed low molecular weight ester and amide substrates at rates comparable with those of free protease, but degradation of highExpand
Plasma Immunoreactive Pancreatic Cationic Trypsinogen in Cystic Fibrosis: a Sensitive Indicator of Exocrine Pancreatic Dysfunction
The results suggest that in CF infants high levels of circulating trypsin(ogen) persist even in those with complete pancreatic insufficiency, and in older CF patients and those with Shwachman's syndrome, circulate accurately reflects residual pancreatic function. Expand
Structural Basis for the Specific Activation of Human Cationic Trypsinogen by Human Enteropeptidase ”
Human cationic trypsinogen is activated by human enteropeptidase much more readily than bovine trypsinogen, the ratios k,,,/K,,, being 330 and 11 mr+-’ s’, respectively. Conversely, porcineExpand
Seed culture was prepared by transferring loopfuls of surface growth from an agar slant into 500ml Erlenmeyer flasks containing 100-ml portions of Nutrient medium composed of Tryptone 0.5 %, maltExpand
Insecticidally effective peptide
The peptide obtained can be utilized as a new method for controlling invertebrate insect pests such as insects by transforming a gene in the venom and preparing a transformed plant having insecticidal actions. Expand
Early Photoinduced Enzymes of Photoinduced
Some nonphotosynthetic microorganisms synthesize carotenes in response to light. Previous experiments demonstrated that the enzymes necessary for the synthesis and metabolism of phytoene wereExpand